Protein Alignment CG4476 and Slc6a18

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_058859.2
• Gene: Slc6a18 / 29323
• RGDID: 69352
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 191/631 - (30%)
• Similarity: 297/631 - (47%)
• Gaps: 125/631 - (19%)

  Fly    51 RDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFS 115
            |..|.:.|::|:|||..:|||||:||||:....:|||||||||.:.|...|.|::|:|:.:||..
  Rat    17 RPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIALVFEGIPLFYIELAIGQRL 81

  Fly   116 SRGIVQVF-DFAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREEWGDGC 179
            .||.:.|: ..:|.:.|||........:::.||.:::...|.:|.:||...||||.|
  Rat    82 RRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLNSFQHPLPWSTC-------- 138

  Fly   180 VSASGGQPLQ----GQLSRNFSSSTQLYL-QRIVLNETDSLEEGIGYPSGSLALMLGISWLTVTL 239
                   ||.    |.:....||.|..|. .|..||.|..: ...|.....|.|.|...|.||.|
  Rat   139 -------PLDLNRTGFVQECQSSGTVSYFWYRQTLNITSDI-SNTGTIQWKLFLCLVACWTTVYL 195

  Fly   240 IIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQV 304
            .:|||::|:||..|..|||||:|:.|.|:|.||||||.:|:.|..||..:.|..|:||.:|.||:
  Rat   196 CVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLTYLFTPNMKILQNPRVWLDAATQI 260

  Fly   305 FFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGILG-NLAHESG---TKD 365
            ||||::.||..|.::|||:..:|..:||..:..:::.|||.:.:.||.|:| ..:::.|   .::
  Rat   261 FFSLSLAFGGHIAFASYNQPRNNCEKDAVTIALVNSMTSLYASITIFSIMGFKASNDYGRCLDRN 325

  Fly   366 IASVVK-----------------------------------------------AGPGLAFISYPD 383
            |.|::.                                               :|||||||.:.:
  Rat   326 ILSLINEFDFPELSISRDEYPSVLMYLNATQPERVARLPLKTCHLEDFLDKSASGPGLAFIVFTE 390

  Fly   384 AIAKFKMFP--QVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFV---NVKLWIIVVSLSVIGF 443
            |:..   .|  .|:|:|||.|||.||:.|..|.:..::|.|.|..:   .|....:...:..|.|
  Rat   391 AVLH---MPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLFDMGILPKGVPKETMTGVVCFICF 452

  Fly   444 LVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRI 508
            |..:.:....|.:.:.:.|....:...::.|..|::.|..:||.||.|.|.|:|...:.|.|:::
  Rat   453 LSAICFTLQSGSYWLEIFDSFAASLNLIIFAFMEVVGVIHVYGIKRFCDDIEWMTGRRPSLYWQV 517

  Fly   509 CWSIVTPLVML-VILVY-SLLTMRPLSYNG-----QEFP----LVYRVVGW----C--------- 549
            .|.:|:|:::. :.|.| .||.....||..     :.||    .:|  .||    |
  Rat   518 TWRVVSPMLLFGIFLSYIVLLAQSSPSYKAWNPQYEHFPSREEKLY--PGWVQVTCVLLSFLPSL 580

  Fly   550 -VSGCIIGQLFY-----WAGYANFKQPKGSLKSRINNSIKPHSDWG 589
             |.|..:.||.:     |.            .:.:.:::||....|
  Rat   581 WVPGIALAQLLFQYRQRWK------------NTHLESALKPQESRG 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	172/537 (32%)
Slc6a18	NP_058859.2	SLC6sbd_B0AT3	16..591	CDD:212086	186/594 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810