Protein Alignment CG4476 and Slc6a15

DIOPT Version :10

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_758824.1
• Gene: Slc6a15 / 282712
• RGDID: 628664
• Length: 729
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 192/593 - (32%)
• Similarity: 305/593 - (51%)
• Gaps: 102/593 - (17%)

  Fly    38 ALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGK 102
            |.:.||:..:|.|   |.|.|:::::.:..|||||||||||:...:|||||:|:|||::|.|:|.
  Rat    51 AEDGSEVDDERPA---WNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGI 112

  Fly   103 PIYYMEMLLGQFSSRGIVQVFDF-APLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASEL 166
            |::::|:.:||...||.:.|::: :|.:.|:|:|..:....:|.||..::..||.||..||...|
  Rat   113 PLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPL 177

  Fly   167 PWSFCREEWGDGCVSASGGQPLQGQLSRNF-------SSSTQLYLQRIVLNETDSLEEGIGYPSG 224
            ||..|               ||....|..:       ||:|..|..|..|..:.|:.|..|....
  Rat   178 PWDQC---------------PLVKNASHTYIEPECEKSSATTYYWYREALAISSSISESGGLNWK 227

  Fly   225 SLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWE 289
            ....:|. :|:.|.|.:|:|::||||..|..:||||||:...|:|:|.|.|:.||:.:..||:.|
  Rat   228 MTGCLLA-AWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLE 291

  Fly   290 KLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGIL 354
            .:|||:||..|.|||||:|.:.||.:|.:||||:..:|.:.||.:|:.::.|||:|:.:::|.:|
  Rat   292 MMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVL 356

  Fly   355 G---NLAHESGTK--------------------------------------DIASVVK------- 371
            |   |:.:|....                                      ||...||
  Rat   357 GFKANIVNEKCISQNSEMILKLLKTGNVSWDVIPRHINLSAVTAEDYHVVYDIIQKVKEEEFAVL 421

  Fly   372 ---------------AGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTV 421
                           .|.|||||::.:|:..|...| .:|::||.||..||:||..|.:..|:|.
  Rat   422 HLKACQIEDELNKAVQGTGLAFIAFTEAMTHFPASP-FWSVMFFLMLINLGLGSMFGTIEGIITP 485

  Fly   422 LKDQFVNVKLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYG 486
            :.|.| .|:..|:.|...::.|.:||:::...|.:.:|:.|.:..|...|:..|.|.|||.::||
  Rat   486 VVDTF-KVRKEILTVICCLLAFCIGLMFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYG 549

  Fly   487 TKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTM--RPLSYN-------GQEFPLV 542
            ..:..:|...||....|.||...|..::||:::.:|:.|::.|  .|..||       .:|| |.
  Rat   550 IDKFLEDLTDMLGFAPSKYYYYMWKYISPLMLVTLLIASIVNMGLSPPGYNAWIKEKASEEF-LS 613

  Fly   543 YRVVGWCV 550
            |.:.|..|
  Rat   614 YPMWGMVV 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	176/544 (32%)
Slc6a15	NP_758824.1	SLC6sbd_SBAT1	61..640	CDD:212091	189/583 (32%)