Protein Alignment CG4476 and dat-1

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 192/593 - (32%)
• Similarity: 310/593 - (52%)
• Gaps: 66/593 - (11%)

  Fly    46 PDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEML 110
            |...||:.|...|:||:|.:..:|.|||:||||:...:||||.|||||.:::.:.|.|::|||:.
 Worm    35 PKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELC 99

  Fly   111 LGQFSSRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFCREE 174
            |||:..:|.:..:. ..||.:|:||..:|....:..:|..::|..|.|.:.||:..|||:.|...
 Worm   100 LGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASCNNS 164

  Fly   175 WG-----------DG---CVSASGGQPLQGQLSRNFSSSTQLYLQ-------------RIVLNET 212
            :.           ||   |.||:     |...:...|::.:.:.:             .::.:.|
 Worm   165 YNSPACYEPHWSEDGTAMCRSAN-----QSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIRSVT 224

  Fly   213 DSLEEGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAY 277
            |     :|.....:||.|.:.:|.....:.:|:.:|||..:..|||||||:.||.:|.:||||..
 Worm   225 D-----LGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQ 284

  Fly   278 DGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFT 342
            :|:.|:|.|.:|.|..|.||.:|.|||||||...|||::.|||||.|.:|||.||...:.::..|
 Worm   285 NGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCAT 349

  Fly   343 SLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLG 407
            |.|||.:||.:||.::.:|| |.|.:|.:.||||.|:.||:|::.....| .:|:|||.||..||
 Worm   350 SFLSGFVIFSVLGYMSCKSG-KPIEAVAQEGPGLVFVVYPEALSTMPYAP-FWSVLFFLMLMTLG 412

  Fly   408 VGSNVGMVSCIMTVLKDQFVNVK--LWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVS 470
            :.|:.|....|:|.|.|:|..:|  ..:.|..|.....::|:...|.||..|:..:..:|.|:..
 Worm   413 LDSSFGGSEAIITGLSDEFPILKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGL 477

  Fly   471 LVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTMRPLSYN 535
            |::...|.:.:.:|||.::...|.:.|:..:..||::.|||...|.::|.::..:.:..:.|:|.
 Worm   478 LIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKFCWSCAAPFILLSMITSNFINYQALTYQ 542

  Fly   536 GQEFPLVYRVVG--WCVSGCIIGQLFYWAGYANFKQPKGS------------LKSRINN------ 580
            ...:|....|:|  :.:||.....|   .|...|...:|:            .:.|.|.
 Worm   543 DYTYPTAANVIGIIFALSGASFIPL---VGIYKFVNARGNTISEKWQRVTMPYRKRPNQTEYIPI 604

  Fly   581 -SIKPHSD 587
             :.:||||
 Worm   605 PTTQPHSD 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	172/503 (34%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	184/565 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820