Protein Alignment CG4476 and dat-1

DIOPT Version :10

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 95/453 - (20%)
• Similarity: 145/453 - (32%)
• Gaps: 181/453 - (39%)

  Fly     6 KEQSLSGVSSEIKKR------------------AKRNTLSSLP----------------QETQPL 36
            |..|.:...|||||:                  :.|.|.:||.                :....|
 Worm   168 KRASRASKPSEIKKKKSIQRGRDISRLASVANQSDRKTCTSLSFSGRTSTSKTASTIEIESKSDL 232

  Fly    37 RKVRIIVNDPYATDDSSSDEEELKV-------PKPRKMKRIVREINFPSMEVSEQPSESSSQDST 94
            ::.|     .::.|..|..|:..:|       |..|.:..::.|        ||..|:|.|||.|
 Worm   233 QEHR-----SFSFDSRSGGEKPKRVSSSSRFTPGSRTIASVLSE--------SESESDSPSQDLT 284

  Fly    95 -----------------------KTDGKIAV------------------SASPAVPRKKPVGVRQ 118
                                   .||....|                  ||..||...||..:..
 Worm   285 ARGSSSVSWHEKAEIVECNVLQCATDEAPEVMETNFVLDAEPVSRLKEHSAVEAVQDIKPKELEM 349

  Fly   119 RKWGKWAAEIRDPIKKTRTWLGTFDTLEEAAKAYDAKKLEFDAIVAGNVSTTKRDVSSSETSQCS 183
            ....:..:|..|.:..    |.|.|:..|..:|:.|.|     .|..|:   ..|::..||.:.|
 Worm   350 DNEDETESEGDDFVDA----LYTIDSESENDEAFQATK-----EVQKNL---YNDITEQETEKIS 402

  Fly   184 R------------------SSPVVP----VEQDDTSASALTC--------VNNP-DDVSTVAPTA 217
            .                  ||||..    :.||..:||.::.        .:|| .|:|.:....
 Worm   403 NNFSVDETKCAATSELHLSSSPVYKSDELIHQDPWAASEISSGTHSYSNGFSNPLYDISGIQEHQ 467

  Fly   218 PTPNVPAGGNKETLFDFDFTNL-------------QIPDFGFLAEEQQDLDFDCF---LADD--- 263
            .:..|.:..:.|::..:...||             .||      |..:|:|.:.|   |.:|
 Worm   468 ESEEVESSCDTESIKTWTNGNLLGLKPSKPKIIAETIP------EIVEDIDSETFQEHLREDYKA 526

  Fly   264 QFDDFGL---LDDIQ-GFEDNGPSALPDFDFADVEDLQLAD----SSFGFLDQLAPINISCPL 318
            .||.|..   ||.:: .|:.:  ..||..:.    .|:|.|    |||    ||.|..|:..|
 Worm   527 PFDWFTSSPPLDHMKISFKSS--ETLPSSEL----QLKLPDEYTFSSF----QLVPETIATSL 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	81/373 (22%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	95/453 (21%)