Protein Alignment CG4476 and slc6a6

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 199/586 - (33%)
• Similarity: 322/586 - (54%)
• Gaps: 50/586 - (8%)

  Fly    29 LLKPS--LLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLI 91
            :||||  ..|......|.......|:.|.|.::|::|.....:|||||||||:...:||||||||
 Frog    17 ILKPSPGKSPGTRPEDEADGKPPQREKWASKIDFVLSVAGGFIGLGNVWRFPYLCYKNGGGAFLI 81

  Fly    92 PYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFD-FAPLMRGVGYAQLLALGVLATYYASVMALTL 155
            ||.:.||..|.|::::|::||||:|.|.:..:: ..|:..|:|||.::.:.:|..||..::|..:
 Frog    82 PYFIFLFGGGLPVFFLEVVLGQFTSEGGITCWEKICPVFTGIGYASIVIVSLLNVYYIVILAWGV 146

  Fly   156 RYFFDSFASELPWSFCREEWG-DGCVS---ASGGQPLQGQLSRNFSSSTQLYLQRIVLNETDSLE 216
            .|.|.||..:|||:.|.:.|. :.||.   ...........|.||:|....:.:..||:.:..::
 Frog   147 YYLFQSFQGQLPWALCHQPWNTESCVEDTFRKNWTMWMSMNSTNFTSPVTEFWEHKVLSLSKGID 211

  Fly   217 EGIGYPSGSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVM 281
            : :|.....|||.|.::|:.....|.:||:|:||..|..|.||::::.:||:|.:|||||.:|:.
 Frog   212 D-VGVLKWDLALCLLLTWVICFFCIWKGVRSTGKVVYFTATFPFIMLLVLLIRGVTLPGAAEGIK 275

  Fly   282 YFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLS 346
            ::|.|...:|.:||||.:|.||:|||.|:|.|.:....|||::.:|.|||..::..|::.||.:|
 Frog   276 FYLYPDITRLADPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVS 340

  Fly   347 GVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSN 411
            |..||.:||.:|.|.|. |||.|.::|||||||:||.|::...: |..:::|||.||.:||:.|.
 Frog   341 GFAIFSVLGFMAQEQGV-DIADVAESGPGLAFIAYPKAVSMMPL-PSFWAILFFIMLLLLGLDSQ 403

  Fly   412 VGMVSCIMTVLKDQFVNV-------KLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFV 469
            ...|...:|.|.|.:.:.       :::|.||..  :.:|:||..:|.||.::..|.|::..:.|
 Frog   404 FVEVEGQITSLVDLYPSFLRKGYRREIFIAVVCF--LSYLLGLTMVTEGGMYVFQLFDYYAASGV 466

  Fly   470 SLV-SAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTMRPLS 533
            .|: .|.||.:||.|:||..:...:.|.|:..|...:.:..|:::|||:.:...::||....||:
 Frog   467 CLLWVAFFECVAVAWVYGADKFYDNIEDMIGYKPGPWMKWSWTVITPLLCVACFIFSLAKYTPLT 531

  Fly   534 YNGQEFPLVYRV-------VGW--------CVSGCIIGQLFYWAGYANFKQPKGSLKSRINNSIK 583
            ||      .|.|       :||        |:...::..:.         :..|||..||.....
 Frog   532 YN------KYYVYPDWAIGLGWVLALSSMICIPLVVVFHIV---------RSDGSLIERIKAVTA 581

  Fly   584 P 584
            |
 Frog   582 P 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	175/486 (36%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	192/560 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920