Protein Alignment CG4476 and slc6a1

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002941943.4
• Gene: slc6a1 / 100491859
• XenbaseID: XB-GENE-5824076
• Length: 622
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 197/584 - (33%)
• Similarity: 316/584 - (54%)
• Gaps: 61/584 - (10%)

  Fly    26 GEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFL 90
            ||.|    .||...:..:...|   |..|....:||:||:..::|||||||||:...:|||||||
 Frog    53 GETL----YLPFGQKKKKADDD---RGTWKGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFL 110

  Fly    91 IPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFDFAPLMRGVGYAQLLALGVLATYYASVMALTL 155
            |||.:.|...|.|::::|..||||:|.|.:.|:..||:.:|||.|.::....|..||..::|..|
 Frog   111 IPYFLTLVFAGIPLFFLETALGQFTSIGGLGVWKLAPMFKGVGMAAVVLSFWLNIYYIVIIAWAL 175

  Fly   156 RYFFDSFASELPWSFCREEWG-DGCVSASGGQPLQGQLSRNFSSSTQLYLQRIVLNETDSLEE-- 217
            .|.|:||:|.|||..|...|. :.|.|             |:|           ||:|.:|..
 Frog   176 YYLFNSFSSTLPWQSCDNSWNTERCFS-------------NYS-----------LNDTSNLTSAV 216

  Fly   218 -------------GIGYPSG---SLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFIL 266
                         |:|.|..   .||..|.::|:.|...|.:||:.:||..|..|.:||.::.||
 Frog   217 TEFWERNMHQMTGGLGEPGNIRWPLACTLALAWIMVYFSIWKGVEWTGKVVYFSATYPYFMLVIL 281

  Fly   267 LVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRD 331
            ..|.:|||||.||:.:::||.:.||...:||.:|.||:|||..:..|.:|...|||.|.:|:|||
 Frog   282 FFRGITLPGAMDGIRFYITPDFSKLSNSEVWMDAATQIFFSYGLGLGSLIALGSYNAFDNNIYRD 346

  Fly   332 ANIVTTLDTFTSLLSGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFS 396
            :.||..:::.||:.:|.:||.|:|.::|.: .|.|..:..:||||||::||.|:.:..|.| |:|
 Frog   347 SIIVCGINSTTSMFAGFVIFSIVGFMSHIT-KKPIQELAASGPGLAFLAYPQAVTQLPMSP-VWS 409

  Fly   397 LLFFAMLFMLGVGSNVGMVSCIMTVLKDQF---VNVKLWIIVVSLSVIGFLVGLIYITPGGQHII 458
            :|||:||.|||:.|....|...:|.|.|::   :..:..:.:..:..|.|::|...||.||.::.
 Frog   410 ILFFSMLVMLGLDSQFCTVEGFITALVDEYPQCLRSRKKVFIAMVCFISFIIGFSNITQGGLYVF 474

  Fly   459 TLMDFHGVTFVSLVSAI-FELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVIL 522
            .|.|::..:.:.|:..: ||.:::.|.||..|..||.|.|:..:..:::::||:..||.:.|.:.
 Frog   475 KLFDYYSASGMCLLFLVFFETVSISWCYGVDRFYQDIEEMIGYQPCSWWKLCWAYFTPCICLGVF 539

  Fly   523 VYSLLTMRPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANF--KQPKGSLKSRINNSIKP 584
            .:|:..|.||:.....:|...:.:||.::   :..:.:..||..:  ...||:|:.|.....:|
 Frog   540 CFSVFEMTPLTLGRYVYPAWGQGIGWLMA---LSSMVFIPGYMLYLLLTTKGTLRQRFREMTQP 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	176/496 (35%)
slc6a1	XP_002941943.4	SLC5-6-like_sbd	62..611	CDD:382020	192/571 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010