Protein Alignment CG4476 and slc6a7

DIOPT Version :10

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002940131.3
• Gene: slc6a7 / 100487063
• XenbaseID: XB-GENE-479449
• Length: 634
• Species: Xenopus tropicalis
• Alignment Length: 602
• Identity: 239/602 - (39%)
• Similarity: 335/602 - (55%)
• Gaps: 47/602 - (7%)

  Fly    32 PSLL--PMALESSELSPD-RKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPY 93
            |.||  |...:.:||..: .:.|.||...|:||:|||...||||||||||:.|..||||||||||
 Frog    15 PDLLMSPSDRDDTELDIEYPEDRGNWSGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLIPY 79

  Fly    94 LVVLFVVGKPIYYMEMLLGQFSSRGIVQVFDFAPLMRGVGYAQLLALGVLATYYASVMALTLRYF 158
            .::|.:.|.|:::||:.||||||.|.:.|:..:||.:|||...||.:.::|.||..::|..|.|.
 Frog    80 FIMLAICGIPLFFMELSLGQFSSLGPLAVWKISPLFKGVGMGMLLIVALVAIYYNMIIAYVLFYL 144

  Fly   159 FDSFASELPWSFCREEWG-DGC----VSASGGQPLQGQLSRNFSSSTQLYLQRIVLNETDSLEEG 218
            |.|..|.|||..|...|. |.|    |..:....|...:|...|.|.: |..|.||:...|  .|
 Frog   145 FASLTSSLPWEHCGNWWNTDLCLDHHVIRASNSALLVNISNTVSPSEE-YWSRYVLHIQGS--SG 206

  Fly   219 IGYPS---GSLALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGV 280
            ||.|.   ..|.|.|.:||..|.|.|::|||||||..|..|.|||:::.:||:|.:||.||:.|:
 Frog   207 IGDPGQLRWKLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPYIILVMLLIRGVTLEGAWIGI 271

  Fly   281 MYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLL 345
            .::||||:|.||..:||..|..|:|:||.|.||.::.::|||.|..|:|||..|||..:.|||:|
 Frog   272 KFYLTPQFEHLLTSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAFTSIL 336

  Fly   346 SGVIIFGILGNLAHESGTKDIASVVKAGPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGS 410
            :|..||.:||.::.|.|. .:..|.||||||||:.||.|:....:.| .:|.|||.||..||:.|
 Frog   337 AGFAIFSVLGYMSQELGV-PVDQVAKAGPGLAFVVYPQAMTMLPLSP-FWSFLFFFMLLTLGLDS 399

  Fly   411 NVGMVSCIMTVLKDQF---VNVKLWIIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLV 472
            ....:..|:|.:.|:|   :..|..:....:.|..||:|||..|.||.:.:.|:|.:...|..||
 Frog   400 QFAFMETIVTAITDEFPYYLRPKKAVFSAIICVALFLLGLILATDGGMYWLVLLDDYSAGFGLLV 464

  Fly   473 SAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLTMRPLSYNGQ 537
            ..|...::|..:||.|..|:|.:.||..|...|::.||..::|:.::.:|.||:|..:|..|...
 Frog   465 IVITFCLSVSRVYGIKNFCRDIQMMLGFKPGLYFKACWIFLSPVTLMCLLAYSILKYQPSQYGSY 529

  Fly   538 EFPLVYRVVGWCVS--GCI---IGQLFYWAGYANFKQPKGSLKSRINNSIKPHSDWGPS------ 591
            :|||....:|..:.  .|:   ||.|     .|..|: :|||..||..:.:|..|||||
 Frog   530 KFPLWSEALGILMGLLSCMMIPIGML-----VAILKE-EGSLWERIRQASRPAMDWGPSMEENRT 588

  Fly   592 -----------DPKKLM 597
                       .||.||
 Frog   589 GMYVNTLAGSQSPKPLM 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	203/484 (42%)
slc6a7	XP_002940131.3	SLC5-6-like_sbd	37..581	CDD:444915	226/554 (41%)