Protein Alignment CG4476 and slc6a19a.2

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002665492.2
• Gene: slc6a19a.2 / 100334171
• ZFINID: ZDB-GENE-141210-16
• Length: 647
• Species: Danio rerio
• Alignment Length: 650
• Identity: 192/650 - (29%)
• Similarity: 313/650 - (48%)
• Gaps: 109/650 - (16%)

  Fly    39 LESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKP 103
            ||..||. :...|..|.:..:::::|:...||||||||||:....:|||||:||:|::|.:.|.|
Zfish    22 LEKLELQ-EAGERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIP 85

  Fly   104 IYYMEMLLGQFSSRGIVQVF-DFAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASELP 167
            :.::|..:||...||.|.|: ...|.:.|||.|.:|...::..||.:::|..:.|||:||...||
Zfish    86 LLHLEFAIGQRLRRGSVGVWRSINPYLLGVGIASMLVSFIVGMYYNTIIAWVMWYFFNSFQDPLP 150

  Fly   168 WSFCREEWGDGCVSASGGQPLQGQLSR-------NFSSSTQLYLQRIVLNETDSLEEGIGYPSGS 225
            ||.|               |:.|  ||       ..||....:..|..||.|..:|:     ||.
Zfish   151 WSQC---------------PING--SRTGFVSECERSSPVDYFWYRKTLNTTPHIED-----SGG 193

  Fly   226 L----ALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTP 286
            |    .|.|..:|..:.:..|||::::|||.|:.:..||:|:.|.|:|.|||.|:..|:.:..||
Zfish   194 LQWWMVLSLLCAWTVLWVCCIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVSGIKFLFTP 258

  Fly   287 QWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIF 351
            ...:||:||.|.:|..|||||.::.||.:|.:||||...:|..:||.|::.::..||:.:.::|:
Zfish   259 DVNELLDPQTWLDAGAQVFFSFSLAFGGLIAFSSYNSVHNNCEQDAVIISIINGMTSIYAAIVIY 323

  Fly   352 GILGNLAHE------SGTKDIASVVKA-------------------------------------- 372
            .|:|..|.|      :|  :|.|::.|
Zfish   324 SIIGFRATERFDDCLNG--NILSLLNAFDLPEGSIIEGNYTEAIQQLNISRPDIIQELQLKTCDM 386

  Fly   373 ---------GPGLAFISYPDAIAKFKMFPQVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVN 428
                     |.|||||.:.:||.|..:.| ::|:|||.|||.||:.:..|.:..::..|:|..:.
Zfish   387 QTFLSQGVEGTGLAFIVFTEAITKMPVSP-LWSVLFFIMLFCLGLSTMFGSIEGVVVPLQDLDIL 450

  Fly   429 VKLW---IIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRL 490
            .|.|   .....:.|:.|...:|:....|::.:.|.|...|:...|:.|..|::||.::||..|.
Zfish   451 PKNWPKEAYTALVCVVSFAFAIIFAQGSGEYWLALFDGFAVSIPLLIIAFCEMMAVSYVYGIDRF 515

  Fly   491 CQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVYSLLT--MRPLSY-----NGQEFPL--VYRVV 546
            ..|.::|:..|.:.:::..|.:::||::|||.::..:|  .:.|:|     ..:.||.  |....
Zfish   516 NDDIKFMIGHKPNIFWQATWRLISPLIVLVIFLFYFVTTVSKKLTYIAWDPESENFPTLSVLPYP 580

  Fly   547 GWCVSGCIIGQLFYWAGYANFKQPKGSLKSRI-NNSIKPHSDWGPSDPKKLMDYQMFLRNKDEEN 610
            ||     |...:|..||......|..:|...| |...|.........|..:.|....:...::.|
Zfish   581 GW-----ISAIIFILAGIPVLVIPTVALVRLIRNRCCKKEETHATETPYSISDRVQMMEETEQNN 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	167/541 (31%)
slc6a19a.2	XP_002665492.2	SLC5-6-like_sbd	33..613	CDD:294310	184/609 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810