Protein Alignment CG4476 and slc6a19

DIOPT Version :10

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001120585.1
• Gene: slc6a19 / 100145739
• XenbaseID: XB-GENE-5870378
• Length: 636
• Species: Xenopus tropicalis
• Alignment Length: 709
• Identity: 195/709 - (27%)
• Similarity: 319/709 - (44%)
• Gaps: 175/709 - (24%)

  Fly     4 LKTEILVSGGLPKLETSRCAGSGEALLKPSLLPMALESSELSPDRKARDNWGSSLEFLMSCIALS 68
            |:..|.....|.||||..   :||                       |..|.:..:::::||...
 Frog    11 LENRIQTYEELEKLETEE---AGE-----------------------RPQWDNKAQYMLTCIGFC 49

  Fly    69 VGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGKPIYYMEMLLGQFSSRGIVQVFD-FAPLMRGV 132
            ||||||||||:....:|||||:||:|::|...|.|:.::|..:||...:|.|.|:. ..|.::||
 Frog    50 VGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLHLEFAIGQRLRKGSVGVWSTIHPTLKGV 114

  Fly   133 GYAQLLALGVLATYYASVMALTLRYFFDSFASELPWSFC-----REEWGDGCVSASGGQPLQGQL 192
            |.|.:|...::..||.:::|..:.|||:||...||||.|     |.|:...|..
 Frog   115 GIASMLVSFLVGLYYNTIIAWVMWYFFNSFQEPLPWSVCPLNANRTEYVSECAR----------- 168

  Fly   193 SRNFSSSTQLYLQRIVLNETDSLEEGIGYPSGS----LALMLGISWLTVTLIIIRGVKSSGKAAY 253
                |||...:..|..||.:..:::     ||:    |.|.|..:|..:.:..|||::::|||.|
 Frog   169 ----SSSVDYFWYRETLNTSTKIDD-----SGNLQWWLVLCLACAWGVLYVCTIRGIETTGKAVY 224

  Fly   254 VLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQWEKLLEPQVWYNAVTQVFFSLAVCFGVIIMY 318
            |.:..||:|:.|.|:|.|||.|:.:|::|..||...:|..|..|.:|..|||:|.::.||.:|.:
 Frog   225 VTSTLPYLVLTIFLIRGLTLKGSVNGIIYLFTPDISELANPVTWLDAGAQVFYSFSLAFGGLISF 289

  Fly   319 SSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFGIL---------------------------GN 356
            ||||...:|..|||.|::.::.|||:.|..:|:.|:                           ||
 Frog   290 SSYNSVHNNCERDAVIISVINGFTSVYSATVIYSIIGFRATARYDDCVDSNILSLTNAFDLPEGN 354

  Fly   357 LAHES----------GTKDIASVVK--------------AGPGLAFISYPDAIAKFKMFPQVFSL 397
            :..::          ...|:.|.:|              .|.|||||.:.:||.|..:.| ::|:
 Frog   355 ITQDNYDSMLNHLNQSNSDLVSTLKLETCDLDQILSDGVEGTGLAFIVFTEAITKMPISP-LWSV 418

  Fly   398 LFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNVKLW---IIVVSLSVIGFLVGLIYITPGGQHIIT 459
            |||.|||.||:.|..|.:..::..|.|..:..|.:   .:...:..:.||:.||::...|.:.:.
 Frog   419 LFFIMLFCLGLSSMFGNMEGVLVPLLDLKIIPKSFPKEAVTGLICAVSFLIALIFVLESGNYWLA 483

  Fly   460 LMDFHGVTFVSLVSAIFELIAVGWIYGTKRLCQDAEYMLNIKTSNYYRICWSIVTPLVMLVILVY 524
            |.|....:...|:.|..|:.:|.:|||..|..:|.::|:..|.:.:::..|.:::||:||||.::
 Frog   484 LFDGFAGSIPLLIIAFCEMFSVVYIYGIDRFNEDIKFMIGHKPNIFWQATWRVISPLLMLVIFLF 548

  Fly   525 SLLT--------------------MRPLSYNGQEFPLVYRVVGWCVSGCIIGQLFYWAGYANFKQ 569
            ..:.                    .:|.||....:.::..:.|  |...:|      ..||.:|
 Frog   549 YFVVKVTQKLEYITWDPDYEQFPKSKPESYPAWVYAIIVILAG--VPSLVI------PVYAIYK- 604

  Fly   570 PKGSLKSRINNSIKPHSDWGPSDPKKLMDYQMFLRN---KDEENSKNVNRRCVCYTAGD 625
                                            |:||   |||:..:.:|...|....||
 Frog   605 --------------------------------FIRNCCTKDEDQREIINAVSVASLNGD 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	166/537 (31%)
slc6a19	NP_001120585.1	SLC6sbd_B0AT1	32..612	CDD:212085	179/641 (28%)