Protein Alignment CG4476 and slc6a18

DIOPT Version :9

• Sequence 1: NP_648293.1
• Gene: CG4476 / 39056
• FlyBaseID: FBgn0035969
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001108369.1
• Gene: slc6a18 / 100141332
• ZFINID: ZDB-GENE-080219-9
• Length: 618
• Species: Danio rerio
• Alignment Length: 623
• Identity: 205/623 - (32%)
• Similarity: 311/623 - (49%)
• Gaps: 136/623 - (21%)

  Fly    38 ALESSELSPDRKARDNWGSSLEFLMSCIALSVGLGNVWRFPFTALENGGGAFLIPYLVVLFVVGK 102
            |.|:|.:    :.|..|.:.:::|::|:..:|||||:||||:.....||||||||||:.|...|.
Zfish     4 ASETSSV----QERPKWDNKVQYLLTCVGFAVGLGNIWRFPYLCQIYGGGAFLIPYLIALVFEGL 64

  Fly   103 PIYYMEMLLGQFSSRGIVQVF-DFAPLMRGVGYAQLLALGVLATYYASVMALTLRYFFDSFASEL 166
            |:.|:|:.:||...:|.:.|: ..:||:.|||.|.::...::..:|.:::|..|.|||.||...|
Zfish    65 PLLYLELAIGQSLRKGSIGVWHSISPLLGGVGVASMVVSFLVGLFYNTILAWVLWYFFHSFEDPL 129

  Fly   167 PWSFC-----REEWGDGCVSASGGQPLQGQLSRNFSSSTQLYLQRIVLNETDSLEEGIGYPSGS- 225
            |||.|     .|.:.:.|||               |:....|..|..||.:..:|:     |||
Zfish   130 PWSQCPINDNLEGYVEECVS---------------STPVNYYWYRQTLNISPDIEQ-----SGSL 174

  Fly   226 ---LALMLGISWLTVTLIIIRGVKSSGKAAYVLALFPYVVMFILLVRALTLPGAYDGVMYFLTPQ 287
               |.|.|..:|..|.:..|||:::.|||.||.|.|||:|:.|.||||||||||.||:.|..||.
Zfish   175 QWTLVLCLATAWSIVYICFIRGIETIGKAVYVTATFPYLVLTIFLVRALTLPGATDGLQYLFTPD 239

  Fly   288 WEKLLEPQVWYNAVTQVFFSLAVCFGVIIMYSSYNRFGHNVYRDANIVTTLDTFTSLLSGVIIFG 352
            |..|..||||.:|.||:||||::.||.:|.:||||...::..|||..|..:::.|||.:.:.||.
Zfish   240 WTLLTNPQVWLDAATQIFFSLSLAFGGLIAFSSYNPKKNDCERDALFVGIINSATSLYASIPIFA 304

  Fly   353 ILGNLA------------------------------HESGTKDIAS--------------VVK-- 371
            |||..|                              ::|..:|:.:              |:|
Zfish   305 ILGFKATSNFNSCVNSNILDLTNAFDIGDRNITIENYDSWLRDLNASDPDRVSSLNLKHCVLKNF 369

  Fly   372 -----AGPGLAFISYPDAIAKFKMFP--QVFSLLFFAMLFMLGVGSNVGMVSCIMTVLKDQFVNV 429
                 :|.|||||.:.:|:.:   .|  ||:::|||.|||.||:.|..|.:..::|.|.|..: |
Zfish   370 LDQSASGTGLAFIVFTEAVIE---MPGSQVWAVLFFVMLFSLGLSSMFGNLEGVLTPLLDLHM-V 430

  Fly   430 KLW----IIVVSLSVIGFLVGLIYITPGGQHIITLMDFHGVTFVSLVSAIFELIAVGWIYGTKRL 490
            ..|    |....:.|:.|||.||:....|.:.:.:.:.:..:...||.|.||:|||...||.||.
Zfish   431 PRWMPKEIFTGLICVVNFLVALIFTLGSGNYWLEIFNSYVGSVPLLVIAFFEIIAVVCFYGIKRF 495

  Fly   491 CQDAEYMLNIKTSNYYRICWSIVTPLVMLVILV-YSLLTMR--PL--SYNGQEFPLVYRVVGWCV 550
            ..|.|.|...:.:.::|.||..::|:::||:|| |.::.::  |.  ::|.|
Zfish   496 SDDIEQMTGRRPNLFWRCCWMGISPVMLLVVLVAYVVVQVQKHPTYPAWNPQ------------- 547

  Fly   551 SGCIIGQLFYWAGYANFKQPKGSLKSRINNSIKPHSDW 588
                         |.||.:.:.          ||:|.|
Zfish   548 -------------YENFPETEE----------KPYSTW 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4476	NP_648293.1	SLC6sbd	52..526	CDD:271359	191/541 (35%)
slc6a18	NP_001108369.1	SLC5-6-like_sbd	12..587	CDD:294310	202/611 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910