DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc45-1 and SUC5

DIOPT Version :9

Sequence 1:	NP_001261618.1	Gene:	Slc45-1 / 39055	FlyBaseID:	FBgn0035968	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_177334.1	Gene:	SUC5 / 843520	AraportID:	AT1G71890	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	119/560 - (21%)
Similarity:	204/560 - (36%)	Gaps:	169/560 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 EMFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSPLLGSISDRCKLR 115
            ::..:::||..::|.:|.:.|.::|.:..:|:.||..|..|...|:.|..:.|::|..||||:.|
plant    33 KIISVASIAAGVQFGWALQLSLLTPYIQLLGIPHKWSSYMWLCGPISGMIVQPIVGYHSDRCESR 97

  Fly   116 WGRRRPIISILSFGIMCGLILVPYGKDLGLLLGDAGYTYAESALNFTSSSGGSVAALVSGEATTG 180
            :|||||.|:.....:...:.|:.:..|:|...||.                      :..:..|.
plant    98 FGRRRPFIAAGVALVAVSVFLIGFAADMGHSFGDK----------------------LENKVRTR 140

  Fly   181 PSASDYKFAVILTILGMVLLDFDADTCQTPARTYLLDMCVPEEQPK--AMTMFALFAGFGGTIGY 243
                    |:|:.:.|...||...:|.|.|.|.:|.|:...:.:..  |...|:.|...|..:||
plant   141 --------AIIIFLTGFWFLDVANNTLQGPCRAFLADLAAGDAKKTRVANACFSFFMAVGNVLGY 197

  Fly   244 AIGGVDWETTHIGSFMGGNIPTVF-------------TLVTIIFAVCYLITVTTFREIPLPLIEQ 295
            |.|...            |:..:|             .|.|..|....|:.:.||
plant   198 AAGSYT------------NLHKMFPFTMTKACDIYCANLKTCFFLSITLLLIVTF---------- 240

  Fly   296 DELLRPLSEQAIKKELKKKNNTIYYIQETTQLELQMASDDPKRLEALQGSYQNGYSPAVEKQGKS 360
                                ::::|:::                        ..:||
plant   241 --------------------SSLWYVKD------------------------KQWSP-------- 253

  Fly   361 QDLETQSDYDAPVSLKAYLKSIF----IMPYSMRMLALTNLFCWMGHVTYCLYFTDFVGEAVFHG 421
                .|.|.:...|...:...||    .|...|.||.:..:..|:....:.||.||::|..|:.|
plant   254 ----PQGDKEEKTSSLFFFGEIFGAVRHMKRPMVMLLIVTVINWIAWFPFILYDTDWMGREVYGG 314

  Fly   422 DPTAAPNSEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKL-MKWFGTKAVY--ISGMIYYGIG 483
            :......|:..  |:.||:.|..|:...:......||.|..: .|..|.|.::  ::.::..|:.
plant   315 NSDGDERSKKL--YDQGVQAGALGLMFNSILLGFVSLGVESIGRKMGGAKRLWGCVNFILAIGLA 377

  Fly   484 MLVL--------------------GLWPTKWGVLVFSTSAGILYGTIFTVPFILVARYHAKNCFS 528
            |.||                    |:   |.||....|..||.....:::||.|.      :.||
plant   378 MTVLVTKSAEHHREIAGPLAGPSSGI---KAGVFSLFTVLGIPLAITYSIPFALA------SIFS 433

  Fly   529 IKNGEIVPLKQARGLGTDVAIISSMVFIAQLIVSLSVGPL 568
            ..:|        .|.|..:.:::..:.|.|:|||.|.|||
plant   434 TNSG--------AGQGLSLGVLNIAICIPQMIVSFSSGPL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_001261618.1	GPH_sucrose	49..568	CDD:273545	117/558 (21%)
Slc45-1	NP_001261618.1	MFS	444..>597	CDD:119392	35/148 (24%)
SUC5	NP_177334.1	GPH_sucrose	29..501	CDD:273545	119/560 (21%)
SUC5	NP_177334.1	MFS	<31..213	CDD:304372	53/221 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I3845
eggNOG	1	0.900	-	-		E1_KOG0637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1689
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1230185at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1050
orthoMCL	1	0.900	-	-		OOG6_100660
Panther	1	1.100	-	-	O	PTHR19432
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X285
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830