DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Slc45-1 and SUT4

DIOPT Version :9

Sequence 1:	NP_001261618.1	Gene:	Slc45-1 / 39055	FlyBaseID:	FBgn0035968	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_172467.1	Gene:	SUT4 / 837530	AraportID:	AT1G09960	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	127/581 - (21%)
Similarity:	223/581 - (38%)	Gaps:	163/581 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 MFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSPLLGSISDRCKLRW 116
            :.|::::|..|:|.:|.:.|.::|.:.::|:.|...|:.|...||.|.|:.||:|..||||..::
plant    43 LLRVASVACGIQFGWALQLSLLTPYVQELGIPHAWASVIWLCGPLSGLFVQPLVGHSSDRCTSKY 107

  Fly   117 GRRRPIISILSFGIMCGLILVPYGKDLGLLLGDAGYTYAESALNFTSSSGGSVAALVSGEATTGP 181
            |||||.|...:..|...::::.:..|:|...||.                         |....|
plant   108 GRRRPFIVAGAVAISISVMVIGHAADIGWAFGDR-------------------------EGKIKP 147

  Fly   182 SASDYKFAVILTILGMVLLDFDADTCQTPARTYLLDMCVPEEQPK--AMTMFALFAGFGGTIGYA 244
            .      |::..:||..:||...:..|.|.|..|.|:...:.:..  |...|:||...|..:|||
plant   148 R------AIVAFVLGFWILDVANNMTQGPCRALLADLTENDNRRTRVANGYFSLFMAVGNVLGYA 206

  Fly   245 IGGVD-W------ETTHIGSFMGGNIPTVFTLVTIIFAVCYLITVTTFREIPLPLIEQDELLRPL 302
            .|..: |      ..|...:....|:.:.|.:..:..|:..:::|:...|:||.
plant   207 TGSYNGWYKIFTFTKTVACNVECANLKSAFYIDVVFIAITTILSVSAAHEVPLA----------- 260

  Fly   303 SEQAIKKELKKKNNTIYYIQETTQLELQMASDDPKRLEALQGSYQNGYSPAVEKQGKSQDLETQS 367
                                                            |.|.|..|::...:
plant   261 ------------------------------------------------SLASEAHGQTSGTD--- 274

  Fly   368 DYDAPVSLKAYLKSIF----IMPYSMRMLALTNLFCWMGHVTYCLYFTDFVGEAVFHGDPTAAPN 428
                    :|:|..||    ..|.::.::.|.....|:|...:.|:.||::|..::.|:|
plant   275 --------EAFLSEIFGTFRYFPGNVWIILLVTALTWIGWFPFILFDTDWMGREIYGGEP----- 326

  Fly   429 SEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKLMKWFGTKAVY-ISG--MIYYGIGMLVLGLW 490
             ....:|.|||..|..|:.:.:....|.|:.:.||.:.:|...|: ||.  |....:||::....
plant   327 -NIGTSYSAGVSMGALGLMLNSVFLGITSVLMEKLCRKWGAGFVWGISNILMAICFLGMIITSFV 390

  Fly   491 PTKWG---------------VLVFSTSAGILYGTIFTVPFILVARYHAKNCFSIKNGEIVPLKQA 540
            .:..|               ||:| |..||.....::||:.|:         ||:...:     .
plant   391 ASHLGYIGHEQPPASIVFAAVLIF-TILGIPLAITYSVPYALI---------SIRIESL-----G 440

  Fly   541 RGLGTDVAIISSMVFIAQLIVSLSVGPLVSW-------MDTTCAVLYASTFLSFLAAIAAM 594
            .|.|..:.:::..:.|.|:|||:..||   |       .....||..|:.|:..:.||.|:
plant   441 LGQGLSLGVLNLAIVIPQVIVSVGSGP---WDQLFGGGNSPALAVGAATGFIGGIVAILAL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_001261618.1	GPH_sucrose	49..568	CDD:273545	118/546 (22%)
Slc45-1	NP_001261618.1	MFS	444..>597	CDD:119392	41/176 (23%)
SUT4	NP_172467.1	GPH_sucrose	38..503	CDD:273545	127/581 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	87	1.000	Domainoid score	I2739
eggNOG	1	0.900	-	-		E1_KOG0637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1689
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1230185at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1050
orthoMCL	1	0.900	-	-		OOG6_100660
Panther	1	1.100	-	-	O	PTHR19432
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X285
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830