Protein Alignment Slc45-1 and slc45a2

DIOPT Version :10

• Sequence 1: NP_648292.1
• Gene: Slc45-1 / 39055
• FlyBaseID: FBgn0035968
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001103847.1
• Gene: slc45a2 / 558311
• ZFINID: ZDB-GENE-050208-97
• Length: 554
• Species: Danio rerio
• Alignment Length: 580
• Identity: 162/580 - (27%)
• Similarity: 264/580 - (45%)
• Gaps: 105/580 - (18%)

  Fly    46 RKTRFEMFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSPLLGSISD 110
            |::|..:....:.....||.||.|.:||:|:||.:|:..:..|:.|.:||::||.:.|::||.||
Zfish    51 RRSRGRLIMHGSAMFGREFCYAVEAAFVTPVLLSVGLPRRLYSLVWLISPILGFILQPVIGSASD 115

  Fly   111 RCKLRWGRRRPIISILSFGIMCGLILVPYGKDLGLLLGDAGYTYAESALNFTSSSGGSVAALVSG 175
            .|:..||||||.|.:|...::.|:.|                                   .::|
Zfish   116 YCRSSWGRRRPYILLLGILMLVGMTL-----------------------------------FLNG 145

  Fly   176 EATTGPSASDYK----FAVILTILGMVLLDFDADTCQTPARTYLLDMCVPEEQPKAMTMFALFAG 236
            :|.|....||..    :|:::.:.|:||.||.||....|.:.||.|:|...::.:.:...||..|
Zfish   146 DAVTTAIISDRNLKRTWAIVVVMFGVVLFDFAADFIDGPIKAYLFDVCSHRDKERGLHYHALLTG 210

  Fly   237 FGGTIGYAIGGVDWETTHIGSFMGGNIPTVFTLVTIIFAVCYLITVTTFREIPLPLIEQDELLRP 301
            .||..||.||.:||..:.:||.:|.....::...::.:.:  .:|...| .||
Zfish   211 LGGACGYLIGAMDWGHSALGSILGSEYQVIYFFSSLTWGI--FLTTHLF-SIP------------ 260

  Fly   302 LSEQAIKKELKKKNNTIYYIQETTQLELQMASDD-PKRLEALQGSYQNGY--------------- 350
              |:.:.||                    .:||. |......:|..||||
Zfish   261 --EKPLMKE--------------------PSSDSCPSASLLPEGPLQNGYGSVCKEPVSLSNVRE 303

  Fly   351 --------SPAVEKQGKSQDLETQSDYDAPVSLKAYLKSIFIMPYSMRMLALTNLFCWMGHVTYC 407
                    :.||....|..:.|.|.    .::||:.|.::..||...|.|.:|:|..|...:...
Zfish   304 RTFSVLSEANAVTPSAKQPNSEVQK----RMTLKSLLSAMVSMPSHYRCLCMTHLLGWTAFLCNM 364

  Fly   408 LYFTDFVGEAVFHGDPTAAPNSEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKLMKWFGTKAV 472
            |:||||:|:.|:.|:|.|..||.|...||.||..||||:.|.|.|.::||.....|:.:.|.|.:
Zfish   365 LFFTDFMGQIVYKGNPYAEHNSTAYATYERGVEVGCWGLCINAVSSALYSYVQRLLLPYIGLKGL 429

  Fly   473 YISGMIYYGIGMLVLGLWPTKWGVLVFSTSAGILYGTIFTVPFILVARYHAKNCFSIKNGEIVPL 537
            |..|...:|:|..::||:|.....|......|::..|::|:||.|::.||.......|.|.....
Zfish   430 YFLGYFMFGLGTGLIGLFPNIVATLTLCCVFGVMSSTLYTIPFNLISEYHKAEEEQRKLGGDGVA 494

  Fly   538 KQARGLGTDVAIISSMVFIAQLIVSLSVGPLVSWMDTTCAVLYASTFLSFLAAI-AAMFV 596
            .:.||.|.|.|.::.||.:||:||...:|.||:...:...|:.:::.:|.:..: .|:|:
Zfish   495 PEGRGTGMDCAALTCMVQLAQVIVGAGLGALVNLAGSVIVVVLSASTVSLIGCLFIAIFM 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_648292.1	MFS_SLC45_SUC	52..591	CDD:340871	158/566 (28%)
slc45a2	NP_001103847.1	MFS_SLC45_SUC	57..549	CDD:340871	158/567 (28%)