Protein Alignment Slc45-1 and Slc45a3

DIOPT Version :9

• Sequence 1: NP_001261618.1
• Gene: Slc45-1 / 39055
• FlyBaseID: FBgn0035968
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_006249827.1
• Gene: Slc45a3 / 304785
• RGDID: 1309764
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 152/629 - (24%)
• Similarity: 261/629 - (41%)
• Gaps: 173/629 - (27%)

  Fly    46 RKTRFEMFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSPLLGSISD 110
            |..:.::..::.:...:|...||..::|.|:||::||:.|.|:|..|:.|::|....|||||.||
  Rat    23 RHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASD 87

  Fly   111 RCKLRWGRRRPIISILSFGIMCGLILVP-YGKDLGLLLGDAGYTYAESALNFTSSSGGSVAALVS 174
            :.:.|:|||||.|..||.|::..|.|:| .|...|||..|
  Rat    88 QWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLCSD------------------------- 127

  Fly   175 GEATTGPSASDYKFAVILTILGMVLLDFDADTCQTPARTYLLDMC-VPEEQPKAMTMFALFAGFG 238
                |.|      ..:.|.|||:.||||....|.||....|.|:. .|:...:|.:::|.....|
  Rat   128 ----TRP------LELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLG 182

  Fly   239 GTIGYAIGGVDWETTHIGSFMGGNIPTVFTLVTIIFAVCYLITVTTFREIPLPLIEQDELLRPLS 303
            |.:||.:..:||:|:.:..::|.....:|.|:|:||.:|...|:         |:.::.:|.|
  Rat   183 GCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLICVAATL---------LVAEEAVLGP-- 236

  Fly   304 EQAIKKELKKKNNTIYYIQETTQLELQMASDDPKRLEALQGSYQNGYSPAVEKQGKSQDLETQSD 368
                                            |:..|.|..|       :|.::..|
  Rat   237 --------------------------------PEPAEGLLVS-------SVSRRCCS-------- 254

  Fly   369 YDAPVSLKAYLKSIF--------IMPYSMRMLALTNLFCWMGHVTYCLYFTDFVGEAVFHGDPTA 425
            ..|.::.: .|.::|        .||.::|.|.:..|..||..:|:.|::||||||.::.|.|.|
  Rat   255 CHAGLAFR-NLGTLFPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRA 318

  Fly   426 APNSEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKLMKWFGTKAVYISGMIYYGIGMLVLGLW 490
            .|.:||..:|:.|:|.|..|:.:.......:||.:.:|::.|||::||::.::.:.:......|
  Rat   319 EPGTEARRHYDEGIRMGSLGLFLQCAISLFFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCL- 382

  Fly   491 PTKWGVLVFSTSA---GILYGTIFTVPFILVARYH-AKNCFSIK--------------------- 530
              ...|:|.:.||   |..:..:..:|:.|.:.|| .|..|..|
  Rat   383 --SHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGGSSEDSQTTSFLLG 445

  Fly   531 --------NGEIVP---------------------------------LKQARGLGTDVAIISSMV 554
                    ||.:.|                                 :...||:..|:||:.|..
  Rat   446 PKPGAPFPNGHVGPGGSSILVPPPALCGASACDVSMRVVVGEPPEAKVVTGRGICLDLAILDSAF 510

  Fly   555 FIAQLIVSLSVGPLVSWMDTTCAVLYASTFLSFLAAIAAMFVLY 598
            .::|:..||.:|.:|....:..|.:.::..|..:|...|..|::
  Rat   511 LLSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVF 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_001261618.1	GPH_sucrose	49..568	CDD:273545	145/594 (24%)
		MFS	444..>597	CDD:119392	40/218 (18%)
Slc45a3	XP_006249827.1	MFS_SLC45_SUC	29..548	CDD:340871	149/615 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1230185at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.710