Protein Alignment Slc45-1 and Slc45a1

DIOPT Version :10

• Sequence 1: NP_648292.1
• Gene: Slc45-1 / 39055
• FlyBaseID: FBgn0035968
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_653348.3
• Gene: Slc45a1 / 246258
• RGDID: 708502
• Length: 752
• Species: Rattus norvegicus
• Alignment Length: 702
• Identity: 188/702 - (26%)
• Similarity: 314/702 - (44%)
• Gaps: 185/702 - (26%)

  Fly    39 DYSHVFRRKTRFEMFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSP 103
            |:..:..:::.:|:.....|...|||:||.||::|:|:|||:|:..:..|:.|.:||::||.:.|
  Rat    75 DFEDLHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQP 139

  Fly   104 LLGSISDRCKLRWGRRRPIISILSFGIMCGLILVPYGKDLGLLLGDAGYTYAESALNFTSSSGGS 168
            |||:.||||..|:|||||.|.:|:.|.:.||.|:..|:|:|:.|.|
  Rat   140 LLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALAD------------------- 185

  Fly   169 VAALVSGEATTGPSASDYKFAVILTILGMVLLDFDADTCQTPARTYLLDMCVPEEQPKAMTMFAL 233
                         :|:::|:.::||:.|:||:||.||:...|:..|::|:|.|.:|.:.:.:.||
  Rat   186 -------------TATNHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHAL 237

  Fly   234 FAGFGGTIGYAIGGVDWETTHIGSFMGGNIPTVFTLVTIIFAVCYLITVTTFRE----------- 287
            .||.||..||.:||:.|:.|..|..:||.:..::....|..:|..::|:.:..|
  Rat   238 MAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYIFTAITLSVTTVLTLVSIPERPLRPLGEKRT 302

  Fly   288 ------IPLP-------------------------------------------LIEQDELLRPLS 303
                  :|||                                           .|.:|..|..::
  Rat   303 AMKSPSLPLPPSPPVLLEEGAGDTLPSTTATSLYASFSSPISPPSPLTPKYGSFISRDSSLTGIN 367

  Fly   304 E----------------------------------QAIKKELKKKNNTIYYIQE----------T 324
            |                                  |||.....:..:. :|.||          |
  Rat   368 EFASSFGTSNIDSVLIDCFTAGHDNYLALPSSVPRQAISVSFPRAPDG-FYCQERGLERREGPLT 431

  Fly   325 TQLE---LQMASDD------------PKRL----------------------EALQGSYQNGYSP 352
            ..|:   |::.|.|            |:.|                      :.:.....||...
  Rat   432 LGLDGDVLRVGSLDTSKPRASGILKRPQTLALPDVAGGNGPETSRRRNVTFSQQVANILLNGVKY 496

  Fly   353 AVEKQGKSQDLETQSDYDAPVSLKAYLKSIFIMPYSMRMLALTNLFCWMGHVTYCLYFTDFVGEA 417
            ..|..|.|:..|      .|:||:....:|:.||.::|.|.:.:...|:......|::|||:||.
  Rat   497 ESELTGSSEQSE------QPLSLRRLCSTIYNMPRALRNLCVNHFLGWLSFEGMLLFYTDFMGEV 555

  Fly   418 VFHGDPTAAPNSEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKLMKWFGTKAVYISGMIYYGI 482
            ||.|||.|...|||...|.:||..|||||.|||||.:.||..:.||.:....:.:|....:.:|:
  Rat   556 VFQGDPKAPHASEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEECLSVRTLYFIAYLSFGL 620

  Fly   483 GMLVLGLWPTKWGVLVFSTSAGILYGTIFTVPFILVARYHAKNCFSIKNGEIVPLKQARGLGTDV 547
            |..:..|....:.||...|:.|||:.|:.|:|:.|:..|:....|:..:.:    ...||:|.|:
  Rat   621 GTGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSAD----GTRRGMGVDI 681

  Fly   548 AIISSMVFIAQLIVSLSVGPLVSWMDTTCAVLYASTFLSFLAAI-AAMFVLY 598
            :::|...|:||::|||.:|||.|.:.:...|:|.::.:|||..: :::.|.|
  Rat   682 SLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFASLVSFLGCLYSSLCVTY 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_648292.1	MFS_SLC45_SUC	52..591	CDD:340871	184/679 (27%)
Slc45a1	NP_653348.3	MFS_SLC45_SUC	88..726	CDD:340871	184/680 (27%)