Protein Alignment Slc45-1 and Slc45a1

DIOPT Version :9

• Sequence 1: NP_001261618.1
• Gene: Slc45-1 / 39055
• FlyBaseID: FBgn0035968
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_776135.2
• Gene: Slc45a1 / 242773
• MGIID: 2653235
• Length: 751
• Species: Mus musculus
• Alignment Length: 701
• Identity: 188/701 - (26%)
• Similarity: 311/701 - (44%)
• Gaps: 183/701 - (26%)

  Fly    39 DYSHVFRRKTRFEMFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSP 103
            |:..:..:::.:|:.....|...|||:||.||::|:|:|||:|:..:..|:.|.:||::||.:.|
Mouse    74 DFGDLHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQP 138

  Fly   104 LLGSISDRCKLRWGRRRPIISILSFGIMCGLILVPYGKDLGLLLGDAGYTYAESALNFTSSSGGS 168
            |||:.||||..|:|||||.|.:|:.|.:.||.|:..|:|:|:.|.|
Mouse   139 LLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALAD------------------- 184

  Fly   169 VAALVSGEATTGPSASDYKFAVILTILGMVLLDFDADTCQTPARTYLLDMCVPEEQPKAMTMFAL 233
                         :|:::|:.::||:.|:||:||.||:...|:..|::|:|.|.:|.:.:.:.||
Mouse   185 -------------TATNHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHAL 236

  Fly   234 FAGFGGTIGYAIGGVDWETTHIGSFMGGNIPTVFTLVTIIFAVCYLITVTTFRE----------- 287
            .||.||..||.:||:.|:.|..|..:||.:..::....|..:|..::|:.:..|
Mouse   237 MAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYVFTAITLSVTTVLTLISIPERPLRPLGEKRT 301

  Fly   288 ------IPLP-------------------------------------------LIEQDELLRPLS 303
                  :|||                                           .|.:|..|..::
Mouse   302 AMKSPSLPLPPSPPVLLEEGAGDALPSTTATSLYASFSSPISPPSPLTPKYGSFISRDSSLTGIN 366

  Fly   304 E----------------------------------QAIKKELKKKNNTIYYIQ---ETTQLELQM 331
            |                                  |||.....:..:..|..:   |..:..|.:
Mouse   367 EFASSFGTSNIDSVLIDCFTAGHDNYLALPSSVPRQAISVSFPRAPDGFYCQERGLERREGPLTL 431

  Fly   332 ASD-DPKRLEALQGS------------------------------------------YQNGYSPA 353
            .|| |..|:.:|..|                                          ..||....
Mouse   432 GSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVAGGNGPETSRRRNVTFSQQVANILLNGVKYE 496

  Fly   354 VEKQGKSQDLETQSDYDAPVSLKAYLKSIFIMPYSMRMLALTNLFCWMGHVTYCLYFTDFVGEAV 418
            .|..|.|:..|      .|:||:....:|:.||.::|.|.:.:...|:......|::|||:||.|
Mouse   497 SELTGSSEQSE------QPLSLRHLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVV 555

  Fly   419 FHGDPTAAPNSEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKLMKWFGTKAVYISGMIYYGIG 483
            |.|||.|...|||...|.:||..|||||.|||||.:.||..:.||.:....:.:|....:.:|:|
Mouse   556 FQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEECLSVRTLYFIAYLAFGLG 620

  Fly   484 MLVLGLWPTKWGVLVFSTSAGILYGTIFTVPFILVARYHAKNCFSIKNGEIVPLKQARGLGTDVA 548
            ..:..|....:.||...|:.|||:.|:.|:|:.|:..|:....|:..:.:    ...||:|.|::
Mouse   621 TGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSAD----GTRRGMGVDIS 681

  Fly   549 IISSMVFIAQLIVSLSVGPLVSWMDTTCAVLYASTFLSFLAAI-AAMFVLY 598
            ::|...|:||::|||.:|||.|.:.:...|:|.|:.:|||..: :::.|.|
Mouse   682 LLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTY 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_001261618.1	GPH_sucrose	49..568	CDD:273545	176/658 (27%)
		MFS	444..>597	CDD:119392	49/153 (32%)
Slc45a1	NP_776135.2	GPH_sucrose	83..>293	CDD:273545	82/241 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849634
Domainoid	1	1.000	154	1.000	Domainoid score	I4253
eggNOG	1	0.900	-	-		E1_KOG0637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	360	1.000	Inparanoid score	I2195
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46818
OrthoDB	1	1.010	-	-		D1230185at2759
OrthoFinder	1	1.000	-	-		FOG0000889
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19432
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5076
SonicParanoid	1	1.000	-	-		X285
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.940