Protein Alignment Slc45-1 and Slc45a3

DIOPT Version :10

• Sequence 1: NP_648292.1
• Gene: Slc45-1 / 39055
• FlyBaseID: FBgn0035968
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_666089.1
• Gene: Slc45a3 / 212980
• MGIID: 1922082
• Length: 553
• Species: Mus musculus
• Alignment Length: 628
• Identity: 153/628 - (24%)
• Similarity: 264/628 - (42%)
• Gaps: 171/628 - (27%)

  Fly    46 RKTRFEMFRLSAIAMAIEFAYAAETSFVSPILLQIGVDHKHMSMTWGLSPLIGFFMSPLLGSISD 110
            |..:.::..::.:...:|...||..::|.|:||::||:.|.|:|..|:.|::|....|||||.||
Mouse    12 RHRKAQLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASD 76

  Fly   111 RCKLRWGRRRPIISILSFGIMCGLILVPYGKDLGLLLGDAGYTYAESALNFTSSSGGSVAALVSG 175
            :.:.|:|||||.|..||.|::..|.|:|..   |.|   ||..|.:
Mouse    77 QWRGRYGRRRPFIWALSLGVLLSLFLIPRA---GWL---AGLLYPD------------------- 116

  Fly   176 EATTGPSASDYKFAVILTILGMVLLDFDADTCQTPARTYLLDMC-VPEEQPKAMTMFALFAGFGG 239
               |.|      ..:.|.|||:.||||....|.||....|.|:. .|:...:|.:::|.....||
Mouse   117 ---TRP------LELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAFSVYAFMISLGG 172

  Fly   240 TIGYAIGGVDWETTHIGSFMGGNIPTVFTLVTIIFAVCYLITVTTFREIPLPLIEQDELLRPLSE 304
            .:||.:..:||:|:.:..::|.....:|.|:|:||.:|...|:         .:.::.:|.|
Mouse   173 CLGYLLPAIDWDTSVLAPYLGTQEECLFGLLTLIFLICMAATL---------FVTEEAVLGP--- 225

  Fly   305 QAIKKELKKKNNTIYYIQETTQLELQMASDDPKRLEALQGSYQNGYSPAVEKQ------GKS-QD 362
                                           |:..|.|..|       ||.::      |.: ::
Mouse   226 -------------------------------PEPAEGLLVS-------AVSRRCCPCHVGLAFRN 252

  Fly   363 LETQSDYDAPVSLKAYLKSIFI-MPYSMRMLALTNLFCWMGHVTYCLYFTDFVGEAVFHGDPTAA 426
            |.|         |...|:.:.. ||.::|.|.:..|..||..:|:.|::||||||.::.|.|.|.
Mouse   253 LGT---------LFPRLQQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAE 308

  Fly   427 PNSEAALNYEAGVRFGCWGMAIYAFSCSIYSLSVTKLMKWFGTKAVYISGMIYYGIGMLVLGLWP 491
            |.:||..:|:.|:|.|..|:.:......::||.:.:|::.|||::||::.::.:.:......|
Mouse   309 PGTEARRHYDEGIRMGSLGLFLQCAISLVFSLVMDRLVQKFGTRSVYLASVMTFPVAAAATCL-- 371

  Fly   492 TKWGVLVFSTSA---GILYGTIFTVPFILVARYH-AKNCFSIK---------------------- 530
             ...|:|.:.||   |..:..:..:|:.|.:.|| .|..|..|
Mouse   372 -SHSVVVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDAGGSSGEDSQTTSFLPGP 435

  Fly   531 -------NGEI---------------------VPLK------------QARGLGTDVAIISSMVF 555
                   ||.:                     |.::            ..||:..|:||:.|...
Mouse   436 KPGALFPNGHVGSGSSGILAPPPALCGASACDVSMRVVVGEPPEARVVTGRGICLDLAILDSAFL 500

  Fly   556 IAQLIVSLSVGPLVSWMDTTCAVLYASTFLSFLAAIAAMFVLY 598
            ::|:..||.:|.:|....:..|.:.::..|..:|...|..|::
Mouse   501 LSQVAPSLFMGSIVQLSHSVTAYMVSAAGLGLVAIYFATQVVF 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc45-1	NP_648292.1	MFS_SLC45_SUC	52..591	CDD:340871	150/613 (24%)
Slc45a3	NP_666089.1	MFS_SLC45_SUC	18..537	CDD:340871	150/614 (24%)