Protein Alignment Rdl and gabra1

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_009293960.1
• Gene: gabra1 / 768183
• ZFINID: ZDB-GENE-061013-194
• Length: 470
• Species: Danio rerio
• Alignment Length: 546
• Identity: 158/546 - (28%)
• Similarity: 230/546 - (42%)
• Gaps: 158/546 - (28%)

  Fly    62 ILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPG 126
            ||||....||.|:||..|....||...::|.||..:|:..|::|:|.:|||.|.|.||.: |.|
Zfish    56 ILDSLLDGYDNRLRPGLGERVTEVKTDIFVTSIGPVSDHDMEYTIDVFFRQSWKDERLKF-KGP- 118

  Fly   127 VETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQY 191
            :..|.:.:.....||.|||||.|.|:|..|..|..|:.:|:...|::..::|||:.|.|||:|:.
Zfish   119 MAVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEEGTLLYTMRLTVRAECPMHLED 183

  Fly   192 FPMDRQLCHIEIESFGYTMRDIRYFW-RDGLSSVGMSSE-VELPQFRVLGHRQRATEINLTTGNY 254
            ||||...|.::..|:.||..::.|.| |....||.::.: ..|.|:.::|....:..:..:||.|
Zfish   184 FPMDAHACPLKFGSYAYTRAEVVYVWTRGAAQSVVVADDGSRLNQYDLMGQSVDSGVVQSSTGEY 248

  Fly   255 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNA 319
            ..:.......|.:||::||.|:|..:.||:|.|||||||.:.|||...|||||||||||..|...
Zfish   249 VVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARN 313

  Fly   320 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR--------IQMRKQRFMAIQKIAEQKK 376
            :|||::|..::|.::..|:..||::|:|:|||.|..||        :...||:         :||
Zfish   314 SLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKQK---------KKK 369

  Fly   377 QQLDGANQQQANPNPNA---NVG-GPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHS 437
            :.|...|.........|   |:. .||...:....|                |.
Zfish   370 ESLLKKNNTYTAATATAFAPNIARDPGLATIAKSAP----------------PP----------- 407

  Fly   438 HGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRG 502
               |..||:                                    :||
Zfish   408 ---PTEPKE------------------------------------EPK----------------- 416

  Fly   503 GPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSD 567
                  |.|                         |||.              |..|.:     |.
Zfish   417 ------PKP-------------------------PEAK--------------KTFNSV-----SK 431

  Fly   568 IDKYSRIVFPVCFVCFNLMYWIIYLH 593
            ||:.:||.||:.|..|||:||..||:
Zfish   432 IDRIARIAFPLLFGTFNLVYWATYLN 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	61/184 (33%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	78/325 (24%)
gabra1	XP_009293960.1	LIC	17..455	CDD:455710	156/542 (29%)
		LGIC_ECD_GABAAR_A1	67..260	CDD:349835	65/194 (34%)
		Cys-loop	177..191	CDD:349835	8/13 (62%)