Protein Alignment Rdl and gabra6b

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 538
• Identity: 169/538 - (31%)
• Similarity: 242/538 - (44%)
• Gaps: 136/538 - (25%)

  Fly    58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYR 122
            ||:.|||.....||.|:||.:|||..||...::|.|...:|:|:|::|:|.:|||.|.|.||.:
Zfish    30 NITRILDRLLDGYDNRLRPGFGGPVTEVKTDIFVTSFGPVSDVEMEYTMDVFFRQTWIDDRLKF- 93

  Fly   123 KRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPM 187
            :.| :|.|.:.:..:..||.|||||.|.|:|..|..||.|:..|:..:|:|..::||||.|.|||
Zfish    94 EGP-IEILRLNNLMVSKIWTPDTFFRNGKRSISHNMTTPNKLFRIMQNGTILYTMRLTINAECPM 157

  Fly   188 NLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDG-LSSVGMSSE-VELPQFRVLGHRQRATEINLT 250
            .|..||||...|.::..|:.|.|.:|.|.|:.| |.||.:..| ..|.|:.::|....:..:...
Zfish   158 RLINFPMDGHSCPLKFGSYAYPMSEIVYTWKKGPLFSVEVPQESSSLLQYDLIGQTVSSERLKSN 222

  Fly   251 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMS 315
            ||.|..:.......|.||::|||.|||..:.||::.||||:::.:.|||...|:|||||||||..
Zfish   223 TGEYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVFGITTVLTMTTLSI 287

  Fly   316 STNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLD 380
            |...:|||:||..::|.::..||..||::|:|:|.|.|           |..:|...|.::
Zfish   288 SARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNY-----------FSTLQANKELRR---- 337

  Fly   381 GANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPK 445
                        ||:.........                              |.|.|.
Zfish   338 ------------ANIARAAAAAAA------------------------------ARSDGE----- 355

  Fly   446 QTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNG-GRGGPQSHGP 509
                                  .::.||         ||     ||.|:..:|. .:........
Zfish   356 ----------------------GVLNPL---------DP-----GGVLKKRMNSLSQRSATDRFS 384

  Fly   510 GPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRI 574
            .|.|......|                  :||||:             |.|:|  .|.|||||||
Zfish   385 RPSQSDFHQQG------------------SAVPAN-------------NMLIG--TSIIDKYSRI 416

  Fly   575 VFPVCFVCFNLMYWIIYL 592
            :||:.|..|||:|||:||
Zfish   417 LFPLSFGAFNLVYWIVYL 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	67/184 (36%)
		Neur_chan_memb	274..588	CDD:397193	78/314 (25%)
gabra6b	XP_002667403.3	Neur_chan_LBD	32..239	CDD:280998	79/208 (38%)
		LIC	33..433	CDD:273305	165/532 (31%)
		Neur_chan_memb	246..430	CDD:280999	78/314 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910