Protein Alignment Rdl and gabrg2

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_073790685.1
• Gene: gabrg2 / 553402
• ZFINID: ZDB-GENE-091118-65
• Length: 477
• Species: Danio rerio
• Alignment Length: 602
• Identity: 169/602 - (28%)
• Similarity: 253/602 - (42%)
• Gaps: 170/602 - (28%)

  Fly    19 PLLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLG----------DVNISAILDSFSVSYDKR 73
            |.:|:.|.:...|||    |..:.:||..:....:..          :.:::.||:|....||.:
Zfish    20 PAVTLKLFLWAFLIA----HLPLSSVQLESDDDEVTNKTWVLTPKVYESDVTHILNSLLDGYDNK 80

  Fly    74 VRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIK 138
            :||:.|..|..:...|:|.||..::.:.|::|:|.:|.|.|.|.||.:...  ::.|.:.|..:.
Zfish    81 LRPDIGVKPTVIHTDMFVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNST--MKVLRLNSNMVG 143

  Fly   139 NIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEI 203
            .||:|||||.|.|::..|..||.|..:|:.:.|.|..::||||.|.|.:.|..||||...|.:|.
Zfish   144 KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRILYTLRLTIDAECQLKLNNFPMDEHSCPLEF 208

  Fly   204 ESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMG 268
            .|:||...:|.|.|:.....||......|.||..:|.|..:..:...:|:|..|.......|.||
Zfish   209 SSYGYPKEEIVYKWKRSSVEVGDIRSWRLYQFSFVGLRNTSEVVRTVSGDYVVLTVFFDLSRRMG 273

  Fly   269 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVY 333
            |:.||.|||..|||::||||||:|::|.|||.:||:|||||||||.:....:|||:|||.::|::
Zfish   274 YFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLF 338

  Fly   334 LGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGP 398
            :..||:.|||:|:||.|:.|.   :..||.     .|.:::||:            ||...:
Zfish   339 VSVCFIFVFAALIEYGTLHYF---VSNRKP-----SKKSDKKKK------------NPLLRL--- 380

  Fly   399 GGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVG 463
                                                   .....||  ||..||...:.||.|..
Zfish   381 ---------------------------------------FSSKQAP--TVDIRPRSATAIQMNNA 404

  Fly   464 T----------------RGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPG 512
            |                :.|:.....|::.                       |.|...||
Zfish   405 TQMQERDEEYGYECLDGKDCTSFFCCFEDC-----------------------RSGAWRHG---- 442

  Fly   513 QGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFP 577
                                            .||               |..:.||.|:||.||
Zfish   443 --------------------------------RLH---------------IRVAKIDSYARIFFP 460

  Fly   578 VCFVCFNLMYWIIYLHV 594
            ..|..||::||..||::
Zfish   461 TAFGLFNVVYWFSYLYL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	60/182 (33%)
		Cys-loop	185..199	CDD:349809	6/13 (46%)
		Neur_chan_memb	274..588	CDD:460753	81/329 (25%)
gabrg2	XP_073790685.1	None