Protein Alignment Rdl and gabra4

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001017822.1
• Gene: gabra4 / 550520
• ZFINID: ZDB-GENE-050417-360
• Length: 557
• Species: Danio rerio
• Alignment Length: 611
• Identity: 184/611 - (30%)
• Similarity: 278/611 - (45%)
• Gaps: 83/611 - (13%)

  Fly     1 MSDSKMDKLARMAPLPRTPLLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDS 65
            |..:|.:.:..|.|...:.|| .:|.: .|.|.:.:|..|         ....|...|.:.|||.
Zfish     1 MVSAKKEMVTAMYPTSISTLL-YFLCV-AACIKRISGQIR---------KDEKLYPENFTRILDR 54

  Fly    66 FSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETL 130
            ....||.|:||.:|||..||...:||.|...:|:|:|::|:|.:|||.|.|.||.| :.| ||.|
Zfish    55 LLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWVDRRLRY-EGP-VEIL 117

  Fly   131 SVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMD 195
            .:.:..:..:|.|||||.|.|:|..|..|..|...|:..:|:|..::||||:|.|||.|..||||
Zfish   118 RLNNLMVTKVWTPDTFFRNGKRSVAHNMTAPNRLFRIMKNGTILYTMRLTISAECPMRLVNFPMD 182

  Fly   196 RQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELP-------QFRVLGHRQRATEINLTTGN 253
            ...|.::..|:.|...::.|.|     :.|....||:|       |:.::|....:..:...||.
Zfish   183 GHSCPLKFGSYAYPKTEMIYTW-----TKGPQHSVEVPPESSSLVQYDLIGQTVSSETVKSITGE 242

  Fly   254 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTN 318
            |..:.......|.|||::||.|||..:.||:|.||||:|:.:.|||...|:|||||||||..|..
Zfish   243 YVVMTVYFHLKRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISAR 307

  Fly   319 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY----MAKRIQMRKQRFMAIQKIAEQKKQQL 379
            .:|||:||..::|.::..||..||::|:|:|.|.|    .|:|.:.::.:..|...:.....:..
Zfish   308 HSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNAQAERAKRKQAKAAAAASVKSSTGKNK 372

  Fly   380 DGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAP 444
            |.....|.|.:.|.|:.......:.|..                  |........|.|.....:.
Zfish   373 DTEEVLQQNSDTNGNLRKRVNSNIQPQA------------------ESKKTQRTEASSKSGASSS 419

  Fly   445 KQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGP 509
            |.|::::....|.     ||...|....|         .|.:.|:.....::.:..:..|    |
Zfish   420 KPTLTSQSSSTSE-----GTSSFSSQSRL---------SPSSASQSNAAASSSSASKTTP----P 466

  Fly   510 GPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITP--------S 566
            .|......|          ..|..|..|..:.|.|.|...|::.:|.........|        |
Zfish   467 APPSTPTVP----------DKPSPGTTPAGSAPLHHLLGPKLENIKKKEAKAQPQPAAPATGGAS 521

  Fly   567 DIDKYSRIVFPVCFVCFNLMYWIIYL 592
            .||:|:||:|||.|..||::||::||
Zfish   522 KIDEYARILFPVSFGAFNMVYWVVYL 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	64/189 (34%)
		Neur_chan_memb	274..588	CDD:397193	86/325 (26%)
gabra4	NP_001017822.1	Neur_chan_LBD	49..256	CDD:280998	76/213 (36%)
		Neur_chan_memb	263..543	CDD:280999	86/325 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910