Protein Alignment Rdl and glrbb

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001003587.1
• Gene: glrbb / 445193
• ZFINID: ZDB-GENE-040801-106
• Length: 494
• Species: Danio rerio
• Alignment Length: 539
• Identity: 161/539 - (29%)
• Similarity: 255/539 - (47%)
• Gaps: 107/539 - (19%)

  Fly    60 SAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKR 124
            |.||:...::||.|:|||:.|.|||..|.:::.|..|:.|..||:.::.:.||.|.||||...:.
Zfish    57 SNILNKLLITYDPRIRPNFKGIPVEDRVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPQD 121

  Fly   125 PGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNL 189
            ...::|:|..:..|.:|.||.||.|||.:.||..|..|..:.:..:|.:..|:||::|.|||::|
Zfish   122 FKSDSLTVDPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGDVLISMRLSVTLSCPLDL 186

  Fly   190 QYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEI-NLT--- 250
            ..||||.|.|.:::||||||..|:::.|:.| ..|.| .|:.||||.:   :|...|. |.|
Zfish   187 TLFPMDTQRCKMQLESFGYTTDDLQFMWQSG-DPVQM-DEIALPQFDI---KQEDIEYGNCTKYY 246

  Fly   251 --TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTL 313
              ||.|:.:.......|.:|:|::.:|.|:.|||::||:|||:|.:|:.|||.||:.:||::::.
Zfish   247 AGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGILSVLSLSSE 311

  Fly   314 MSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQ 378
            .:|..:.|||:||||:||::|..|.:..||||:|||.|     ::.:...:.:..::.....|::
Zfish   312 CTSLASELPKVSYVKAIDIWLIACLLFGFASLVEYAVV-----QVMLNSPKLLEAERAKIATKEK 371

  Fly   379 LDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHA 443
            .:|       ..|..|.                   :|   |||..|.|              .:
Zfish   372 AEG-------KTPAKNT-------------------IN---GMGSTPIH--------------VS 393

  Fly   444 PKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHG 508
            ..|....|.......:.::.|...||||.|.::......|    ..|..:|      .|...|..
Zfish   394 TLQVTETRCKKVCTSKSDLRTNDFSIVGSLPRDFELSNFD----CYGKPIE------VGSAFSKS 448

  Fly   509 PGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSR 573
            ........||                  |:..:|:                    ....||.|:|
Zfish   449 QAKNNKKPPP------------------PKPVIPS--------------------AAKRIDLYAR 475

  Fly   574 IVFPVCFVCFNLMYWIIYL 592
            .:||..|:.||::||.:||
Zfish   476 ALFPFSFLFFNVIYWSVYL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	68/188 (36%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	75/313 (24%)
glrbb	NP_001003587.1	LIC	45..493	CDD:455710	159/536 (30%)
		LGIC_ECD	79..264	CDD:475126	69/189 (37%)