DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rdl and NtR

DIOPT Version :9

Sequence 1:	NP_001261617.1	Gene:	Rdl / 39054	FlyBaseID:	FBgn0004244	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	69/339 - (20%)
Similarity:	121/339 - (35%)	Gaps:	104/339 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LIAQETGHKRI--H-TVQAATGGGSMLGDVNISAILDSF---SVSYDKRVRPNYGGPPVEVGVTM 89
            ::.:||..:::  | .:||.  ..||  ..|:|:|...|   |::|::
  Fly   209 IVKEETKTEKLLSHLNIQAE--NASM--PANLSSISFHFQTRSLAYEQ----------------- 252

  Fly    90 YVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGS-EFIKN----IWVPDTFFVN 149
                .|||.:.:|      :....|.|.||.::..      ..|| |..::    ||.|....:|
  Fly   253 ----TSSLLQTRM------HMMMHWRDSRLVWKPE------DFGSLESFEHPDLRIWKPHMNVLN 301

  Fly   150 EKQSYFHIATTSNEFIRVHHSGSIT-RSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYT-MRD 212
            ...........|.| :.|:.:|||| .:..|.:.:.|..:.:.:|.:|..|.||:...|.. ..:
  Fly   302 GALQSMGQVLQSYE-LMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQEN 365

  Fly   213 IRYFWRDGLSSVGMSSEVELP-------------------QFRVLGHRQRATEINLTTGNYSRLA 258
            :...:.|....:..:..|..|                   ::...|..|:.|         ..:|
  Fly   366 VALIYDDQRKPIAPNEHVNTPSGWSFTQMSVVLVENDSQRRYNPKGMMQKMT---------GDVA 421

  Fly   259 CEIQFVRSMGYYLIQIYIP-------------------SGLI----VIISWVSFWLNRNATPARV 300
            .|....|:..:|:...|:|                   |.||    :|.:|...::.|.|:|..|
  Fly   422 IEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRSTRRSSLILIALLIAAWGLMYMTRYASPHYV 486

  Fly   301 ALGVTT--VLTMTT 312
            ...:|.  |:.|||
  Fly   487 PPMMTAYKVIMMTT 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	38/208 (18%)
Rdl	NP_001261617.1	Neur_chan_memb	274..588	CDD:397193	16/64 (25%)
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	51/263 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100