Protein Alignment Rdl and GABRR1

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_002033.2
• Gene: GABRR1 / 2569
• HGNCID: 4090
• Length: 479
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 168/574 - (29%)
• Similarity: 251/574 - (43%)
• Gaps: 163/574 - (28%)

  Fly    35 ETGHKRIHTVQAATGGGSMLGDVNISAILDSFSV----SYDKRVRPNYGGPPVEVGVTMYVLSIS 95
            |..||::..:...:      .|:..|.:..|..:    .:|..:||.:|||.:.|||.:.|.|:.
Human    51 EDAHKQVSPILRRS------PDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLD 109

  Fly    96 SLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSV--GSEFIKNIWVPDTFFVNEKQSYFHIA 158
            |:|||.||||:..|.|.:|.|.||::   |....||:  ....:|.|||||.|||:.|:|:.|..
Human   110 SISEVDMDFTMTLYLRHYWKDERLSF---PSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDT 171

  Fly   159 TTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSS 223
            ||.|..:||...|.:..|:|:|:||.|.|:...||:|.|.|.:||||:.||..|:..:|:.|..|
Human   172 TTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDS 236

  Fly   224 VGMSSEVELPQFRVLG-HRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWV 287
            :.....:.|.||.:.. |.........:||.|:||.......|.:.::|:|.|.|:.|:|::|||
Human   237 LKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301

  Fly   288 SFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG 352
            |||::|.|.||||.||:||||||:|:::..||::|::||:|::|:||...||.||.|:||||.|.
Human   302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVN 366

  Fly   353 YMAKRIQMRKQRFMAIQKIAEQ----------KKQQLDGANQQQANPNPNANVGGPGGVGVGPGG 407
            |:. .:|.||:     ||:.|:          :...||| |......|...|
Human   367 YLT-TVQERKE-----QKLREKLPCTSGLPPPRTAMLDG-NYSDGEVNDLDN------------- 411

  Fly   408 PGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGP 472
                           ..||:|             ..|.:.:
Human   412 ---------------YMPENG-------------EKPDRMM------------------------ 424

  Fly   473 LFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDP 537
                                ::.|:...|..||.
Human   425 --------------------VQLTLASERSSPQR------------------------------- 438

  Fly   538 EAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591
                          |..:.....:.|....|||||||:||..::.|||:||.|:
Human   439 --------------KSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	71/185 (38%)
		Neur_chan_memb	274..588	CDD:397193	79/323 (24%)
GABRR1	NP_002033.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..55		1/3 (33%)
		LIC	75..478	CDD:273305	162/542 (30%)
		Neur_chan_LBD	76..281	CDD:280998	78/207 (38%)
		Neur_chan_memb	288..475	CDD:280999	79/323 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770