Protein Alignment Rdl and Glra2

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001344028.1
• Gene: Glra2 / 237213
• MGIID: 95748
• Length: 452
• Species: Mus musculus
• Alignment Length: 528
• Identity: 175/528 - (33%)
• Similarity: 259/528 - (49%)
• Gaps: 150/528 - (28%)

  Fly    70 YDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGS 134
            ||.|:|||:.||||.|...:::.|..|::|..||:.::.:.||.|.|.||||.:.|. ::|.:..
Mouse    58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD-DSLDLDP 121

  Fly   135 EFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLC 199
            ..:.:||.||.||.|||.:.||..||.|:.:|:..:|.:..|||||:|.||||:|:.||||.|.|
Mouse   122 SMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186

  Fly   200 HIEIESFGYTMRDIRYFW-RDGLSSVGMSSEVELPQF-----RVLGHRQRATEINLTTGNYSRLA 258
            .:::|||||||.|:.:.| .||  .|.::..:.||||     :.||:..:    :..||.::.:.
Mouse   187 TMQLESFGYTMNDLIFEWLSDG--PVQVAEGLTLPQFILKEEKELGYCTK----HYNTGKFTCIE 245

  Fly   259 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPK 323
            .:....|.|||||||:||||.||||:||||||:|.:|.|||||||:||||||||..|.:.|:|||
Mouse   246 VKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPK 310

  Fly   324 ISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQAN 388
            :||||:||:::..|.:.|||:|||||.|.::::    :.:.|:.:::..:::.::.|...:.:.|
Mouse   311 VSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR----QHKEFLRLRRRQKRQNKEEDVTRESRFN 371

  Fly   389 PNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPI 453
            .:                             |.|||         |........|.|.|.:|
Mouse   372 FS-----------------------------GYGMG---------HCLQMKDGTAVKATPAN--- 395

  Fly   454 GFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPP 518
                              ||                              ||
Mouse   396 ------------------PL------------------------------PQ------------- 399

  Fly   519 GGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCF 583
                       ||:   |.:|           :|| |.:::     ...||..||..||:.|:.|
Mouse   400 -----------PPK---DADA-----------IKK-KFVDR-----AKRIDTISRAAFPLAFLIF 433

  Fly   584 NLMYWIIY 591
            |:.|||.|
Mouse   434 NIFYWITY 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	70/188 (37%)
		Neur_chan_memb	274..588	CDD:397193	84/313 (27%)
Glra2	NP_001344028.1	LIC	46..441	CDD:273305	174/526 (33%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	236..241		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2310
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X271
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860