Protein Alignment Rdl and glra4b

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_073805842.1
• Gene: glra4b / 192125
• ZFINID: ZDB-GENE-020402-2
• Length: 575
• Species: Danio rerio
• Alignment Length: 528
• Identity: 180/528 - (34%)
• Similarity: 263/528 - (49%)
• Gaps: 112/528 - (21%)

  Fly    70 YDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGS 134
            ||.|:|||:.||||.|...:::.|..|::|..||:.|:.:.||.|.||||||::.|. ::|.:..
Zfish   140 YDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPD-DSLDLDP 203

  Fly   135 EFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLC 199
            ..:.:||.||.||.|||.:.||..||.|:.:|:..:|::..|||||:..||||:|:.||||.|.|
Zfish   204 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTC 268

  Fly   200 HIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQF-----RVLGHRQRATEINLTTGNYSRLAC 259
            .:::|||||||.|:.:.|.|. ..|.::.::.||||     :.||:..:    :..||.::.:..
Zfish   269 TMQLESFGYTMNDLIFQWLDE-GPVQVADDLMLPQFVLKEEKDLGYCTK----HYNTGKFTCIEV 328

  Fly   260 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKI 324
            :....|.|||||||:||||.|.||:||||||:|.:|.||||.||:||||||||..|.:.|:|||:
Zfish   329 KFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKV 393

  Fly   325 SYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKI-AEQKKQQLDGANQQQAN 388
            ||||:||:::..|.:.|||:|||||.|.:::::.   |:.|...:|: .||:.:...|.......
Zfish   394 SYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQY---KEFFRLRRKLRQEQRNRAASGQAGAAET 455

  Fly   389 PNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPI 453
            .|.:.||.|                                         |.|....|
Zfish   456 KNKSNNVTG-----------------------------------------GTPSRNAQ------- 472

  Fly   454 GFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPP 518
                       |.||...   :|.:....:...:..|..::.:::|  .||.|..... ..|.||
Zfish   473 -----------RQCSACA---REEQLASQNQDLYFPGFGIDTSLSG--DGPLSEAAAM-FAGLPP 520

  Fly   519 GGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCF 583
            |                        |.|.        ||.:........||..||.|||:.|:.|
Zfish   521 G------------------------HALF--------DIRRRFVEQAKRIDTISRAVFPLSFLVF 553

  Fly   584 NLMYWIIY 591
            |:.||:.|
Zfish   554 NVFYWVTY 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	70/187 (37%)
		Cys-loop	185..199	CDD:349809	9/13 (69%)
		Neur_chan_memb	274..588	CDD:460753	90/314 (29%)
glra4b	XP_073805842.1	None