Protein Alignment Rdl and glra3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_021333244.1
• Gene: glra3 / 192124
• ZFINID: ZDB-GENE-020402-1
• Length: 489
• Species: Danio rerio
• Alignment Length: 592
• Identity: 187/592 - (31%)
• Similarity: 293/592 - (49%)
• Gaps: 140/592 - (23%)

  Fly    24 W-LAINMALIAQ---ETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVE 84
            | :.|.::|:|.   |:..:|...:..:.....::|..:          .||.|:|||:.||||.
Zfish    17 WEIGILLSLVASKEPESPRRRAAPMSPSDFLDKLMGRTS----------GYDARIRPNFKGPPVN 71

  Fly    85 VGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVN 149
            |...:::.|..|::|..||:.::.:.||.|.||||||.:.|. ::|.:....:.:||.||.||.|
Zfish    72 VTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD-DSLDLDPSMLDSIWKPDLFFAN 135

  Fly   150 EKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIR 214
            ||.::||..||.|:.:|:..:|::..|||||:|.||||:|:.||||.|.|.:::|||||||.|:.
Zfish   136 EKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200

  Fly   215 YFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYS--RLAC-EIQF--VRSMGYYLIQI 274
            :.|:: ...|.::..:.||||.:    :..:::...|.:|:  :..| |::|  .|.|||||||:
Zfish   201 FEWQE-KGPVQVADGLTLPQFIL----KDESDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQM 260

  Fly   275 YIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFV 339
            ||||.||||:||||||:|.:|.|||||||:||||||||..|.:..:|||:||||:||:::..|.:
Zfish   261 YIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLL 325

  Fly   340 MVFASLLEYATVGYMAKR----IQMRKQRFMAIQKIAEQKKQQLD---GANQQQANPNPNANVGG 397
            .||::|||||.|.:::::    ::.|::|    :|..:...|..|   ..:.::.|.:.:|.
Zfish   326 FVFSALLEYAAVNFVSRQHKELLRFRRRR----KKSGKTFDQTFDEELAESLRRINGSRSAE--- 383

  Fly   398 PGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNV 462
                                       |.:|        |.|.   ..||        :::::.|
Zfish   384 ---------------------------PVYG--------SMGQ---LDQT--------NDMEEEV 402

  Fly   463 GTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGG 527
                        :|.|.. ..|.| .|.|.:..|.|.....|......||
Zfish   403 ------------RESRLS-FTPNA-GKDGAVPKTANNAATTPSEPAVAPG--------------- 438

  Fly   528 GGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY- 591
                                    |..:::.||.......||..||..||:.|:.||:.||::|
Zfish   439 ------------------------KSHEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYK 479

  Fly   592 -LHVSDV 597
             |...||
Zfish   480 ILRHEDV 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	70/187 (37%)
		Cys-loop	185..199	CDD:349809	9/13 (69%)
		Neur_chan_memb	274..588	CDD:460753	87/320 (27%)
glra3	XP_021333244.1	LIC	13..478	CDD:273305	183/582 (31%)