Protein Alignment Rdl and glc-4

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_495489.2
• Gene: glc-4 / 182971
• WormBaseID: WBGene00001594
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 162/615 - (26%)
• Similarity: 251/615 - (40%)
• Gaps: 164/615 - (26%)

  Fly    23 IWLAINMALIAQETGHK-----------RIHTVQAATGGGSMLGDVNISAILDSFSV-----SYD 71
            :::::.:||:...|..|           ..||             .|..|..:..:|     .||
 Worm     5 LYVSVLLALLVSSTAKKSKTKSCKRTAFSRHT-------------TNYQAWREQMTVCDLLQDYD 56

  Fly    72 KRVRPNYGGPP-------VEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVET 129
            ..|||: |..|       |.|..::.:.|||::||..|:|...|.|||.|.|.||.:.:..|:.:
 Worm    57 AAVRPS-GRTPYNDTRGAVMVTTSLNIRSISAVSEKNMEFVAQFRFRQEWYDDRLRFIEHQGLLS 120

  Fly   130 LSVGS-EFI-----KNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMN 188
            ....: |||     :::|:|||||.|||..::|:....|.|:::...|.:....|||:..:|.|:
 Worm   121 SDYRNFEFIHVARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSDGKLIYDRRLTLHLACSMH 185

  Fly   189 LQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGN 253
            |..:|||.|.|.|...|:.||..||.|.|......:...:...||.|.:...:..:......||.
 Worm   186 LSRYPMDHQNCEIAFASYAYTTADIEYIWDVPAIQIHEGANGALPNFEIASFKNASCTSKTNTGT 250

  Fly   254 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTN 318
            ||.|..||:..|...::|:|:||||.::|.::|||:|::..:|.|||.|.:.|:|||.|...:.|
 Worm   251 YSCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMITTSHAIN 315

  Fly   319 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGA- 382
            :.||.:||.||||:::|.|.|.:|.||:|||.|.|:.               |.::.:|....|
 Worm   316 SNLPPVSYAKSIDIWVGACVVFIFFSLIEYAVVNYVG---------------ILDEHRQMKKAAC 365

  Fly   383 -NQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHS-HGHPHAPK 445
             ..:.:|...|.|                                    .|....| ...|...|
 Worm   366 NRSRLSNVIENDN------------------------------------FGESLQSLTFSPQEKK 394

  Fly   446 QTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPG 510
            :.:..||  ..|::...|.         |:.:...
 Worm   395 RLIRRRP--KKNMEMQEGD---------FEAIEMV------------------------------ 418

  Fly   511 PGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAH----LLHPGKVKKVKDINKLLGITPS----- 566
                            ..|||...|..|.....|    |::.|:.|:| ::.:...:..|
 Worm   419 ----------------DRGPPRSAGLMEEGWTFHDTTDLVYIGQRKRV-ELVRWCSVLSSRGRAE 466

  Fly   567 DIDKYSRIVFPVCFVCFNLMYWIIYLHVSD 596
            .||..:||:||:.|:.||..||.|||...|
 Worm   467 RIDIIARIIFPLAFILFNFAYWSIYLEEED 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	63/188 (34%)
		Neur_chan_memb	274..588	CDD:397193	74/325 (23%)
glc-4	NP_495489.2	LIC	26..491	CDD:273305	154/587 (26%)
		Neur_chan_LBD	50..258	CDD:280998	68/208 (33%)
		Neur_chan_memb	271..488	CDD:280999	74/325 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810