Protein Alignment Rdl and glc-3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_504441.1
• Gene: glc-3 / 178930
• WormBaseID: WBGene00001593
• Length: 484
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 180/584 - (30%)
• Similarity: 244/584 - (41%)
• Gaps: 169/584 - (28%)

  Fly    50 GGSMLGDVNISAILDSFSVSYDKRVRP---------NYGGPPVEVGVTMYVLSISSLSEVKMDFT 105
            ||:.....:...|.......||.||||         .:|.  |.|.|.|.:.|||.:.:|.|:::
 Worm    19 GGNCDASSDTEIIKKLLGKGYDWRVRPPGINLTIPGTHGA--VIVYVNMLIRSISKIDDVNMEYS 81

  Fly   106 LDFYFRQFWTDPRLAYRKRPGVET-----LSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFI 165
            :...||:.|.|.|||| ..||..|     |:.|.:    ||:||:||.||||::.|.....|..|
 Worm    82 VQLTFREEWVDGRLAY-GFPGDSTPDFLILTAGQQ----IWMPDSFFQNEKQAHKHDIDKPNVLI 141

  Fly   166 RVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFW--------RDGLS 222
            |:|..|.|..|:|:::..||||:|||:|||.|.|.|::.|:.||..||.|.|        :.||.
 Worm   142 RIHRDGRILYSVRISMVLSCPMHLQYYPMDVQTCLIDLASYAYTENDIEYRWKKTDPVQLKKGLH 206

  Fly   223 SVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWV 287
            |       .||.|.:.............||.||.|...::..|...|||:|:||||.::||:|||
 Worm   207 S-------SLPSFELNNVDTTLCTSKTNTGTYSCLRTVLELRRQFSYYLLQLYIPSTMLVIVSWV 264

  Fly   288 SFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG 352
            ||||:|.|.||||.|||||:|||||..|..||.||.:||.|:|||::|.|...:|.:|||:|.|.
 Worm   265 SFWLDRGAVPARVTLGVTTLLTMTTQASGINAKLPPVSYTKAIDVWIGACLTFIFGALLEFAWVT 329

  Fly   353 YMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNV 417
            |::.|      .|....|....:...|....|....||.        .|...|..|      ..|
 Worm   330 YISSR------SFYKRNKNCSSRNSLLIETKQALIIPNT--------VVAQFPEHP------EEV 374

  Fly   418 GVGMGMGP-----EHGHG------HGHHAHSHGHPHAPKQTV-----SNRPI----GFSNIQQNV 462
            .:|:...|     :.|:|      :||  .:|.:..|.:..:     .||..    .|.||:
 Worm   375 EMGLAQAPDVWIRQSGNGKTVSRVNGH--INHNNDEAAELIIFDAKHKNRRFVWWTNFRNIR--- 434

  Fly   463 GTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGG 527
                      |.:.:|                |.:|
 Worm   435 ----------LIRWIR----------------NRLN----------------------------- 444

  Fly   528 GGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591
                                      |.|..|       ..|..||::||..|||||.:||..|
 Worm   445 --------------------------VDDNAK-------RADLISRVLFPTLFVCFNFVYWTKY 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	72/195 (37%)
		Cys-loop	185..199	CDD:349809	10/13 (77%)
		Neur_chan_memb	274..588	CDD:460753	90/333 (27%)
glc-3	NP_504441.1	LIC	29..475	CDD:455710	177/572 (31%)