Protein Alignment Rdl and Glra1

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001277750.1
• Gene: Glra1 / 14654
• MGIID: 95747
• Length: 457
• Species: Mus musculus
• Alignment Length: 600
• Identity: 185/600 - (30%)
• Similarity: 272/600 - (45%)
• Gaps: 182/600 - (30%)

  Fly     1 MSDSKMDKLARMAPLPRTPLLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDS 65
            ::.||..:.||.||.|.:|                                        |..||.
Mouse    20 LAASKEAEAARSAPKPMSP----------------------------------------SDFLDK 44

  Fly    66 F---SVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGV 127
            .   :..||.|:|||:.||||.|...:::.|..|::|..||:.::.:.||.|.||||||.:.|.
Mouse    45 LMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD- 108

  Fly   128 ETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYF 192
            ::|.:....:.:||.||.||.|||.::||..||.|:.:|:..:|::..|||:|:|.:|||:|:.|
Mouse   109 DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNF 173

  Fly   193 PMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQ-RATEINLTTGNYSR 256
            |||.|.|.:::|||||||.|:.:.|:: ..:|.::..:.||||.:...:. |....:..||.::.
Mouse   174 PMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTC 237

  Fly   257 LACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAAL 321
            :.......|.|||||||:||||.||||:||:|||:|.:|.||||.||:||||||||..|.:.|:|
Mouse   238 IEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASL 302

  Fly   322 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQ 386
            ||:||||:||:::..|.:.||::|||||.|.:                 ::.|.|:.|....:::
Mouse   303 PKVSYVKAIDIWMAVCLLFVFSALLEYAAVNF-----------------VSRQHKELLRFRRKRR 350

  Fly   387 ANPNPNANV-----GGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQ 446
            .:.:|..|:     ||.|.....               ..||||
Mouse   351 HHKSPMLNLFQDDEGGEGRFNFS---------------AYGMGP--------------------- 379

  Fly   447 TVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGP 511
                     :.:|   ...|.|:                   ||....||.|
Mouse   380 ---------ACLQ---AKDGISV-------------------KGANNNNTTN------------- 400

  Fly   512 GQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVF 576
                              ||                |...|..:::.||.......|||.|||.|
Mouse   401 ------------------PP----------------PAPSKSPEEMRKLFIQRAKKIDKISRIGF 431

  Fly   577 PVCFVCFNLMYWIIY 591
            |:.|:.||:.|||||
Mouse   432 PMAFLIFNMFYWIIY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	66/183 (36%)
		Neur_chan_memb	274..588	CDD:397193	86/318 (27%)
Glra1	NP_001277750.1	LIC	7..446	CDD:273305	183/598 (31%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	230..235		2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..410		9/65 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2310
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X271
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860