Protein Alignment Rdl and Gabrg3

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_017177467.1
• Gene: Gabrg3 / 14407
• MGIID: 95624
• Length: 468
• Species: Mus musculus
• Alignment Length: 544
• Identity: 151/544 - (27%)
• Similarity: 239/544 - (43%)
• Gaps: 124/544 - (22%)

  Fly    56 DVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLA 120
            |.:::.||:.....|||::||:.|..|..:.|.:||.||..:|.:.|::.:|.:|.|.|||.||.
Mouse    44 DTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR 108

  Fly   121 YRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASC 185
            :...  ::.|::.|..:..||:|||.|.|.|.:..|..||.|:.:|:.:.|.|..::||||.|.|
Mouse   109 FNST--MKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAEC 171

  Fly   186 PMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLT 250
            .:.|..||||...|.:...|:||...::.|.||.............|.||..:|.|.....:..:
Mouse   172 QLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTS 236

  Fly   251 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMS 315
            .|:|..:....:..|.|||:.||.|||..|.|::||||||:.::|||||..||:|||||||||.:
Mouse   237 AGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTTLST 301

  Fly   316 STNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLD 380
            ....:||::|||.::|:::..||:.|||:|:||||:.|.:   ..||      ..|.::|..||
Mouse   302 IARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYS---SCRK------PTIRKKKTSQL- 356

  Fly   381 GANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPK 445
                    .:|::....|..:.:                         ....:::.....|..|.
Mouse   357 --------LHPDSTRWIPDRISL-------------------------QAPSNYSLLDMRPPPPV 388

  Fly   446 QTVSNRPIGFSNIQQN-----VGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQ 505
            ....|..:.:...:..     :..:.|......::|           .|.|:...    ||
Mouse   389 MITLNNSMYWQEFEDTCVYECLDGKDCQSFFCCYEE-----------CKSGSWRR----GR---- 434

  Fly   506 SHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDK 570
                                                    :|               |..|::|.
Mouse   435 ----------------------------------------IH---------------IDVSELDS 444

  Fly   571 YSRIVFPVCFVCFNLMYWIIYLHV 594
            |||:.||..|:.|||:||:.||::
Mouse   445 YSRVFFPTSFLLFNLVYWVGYLYL 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	57/182 (31%)
		Neur_chan_memb	274..588	CDD:397193	74/318 (23%)
Gabrg3	XP_017177467.1	LIC	50..465	CDD:273305	148/533 (28%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	57/182 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910