Protein Alignment Rdl and Gabra1

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_006532258.1
• Gene: Gabra1 / 14394
• MGIID: 95613
• Length: 553
• Species: Mus musculus
• Alignment Length: 539
• Identity: 157/539 - (29%)
• Similarity: 227/539 - (42%)
• Gaps: 146/539 - (27%)

  Fly    62 ILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPG 126
            |||.....||.|:||..|....||...::|.|...:|:..|::|:|.:|||.|.|.||.: |.|
Mouse   142 ILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKF-KGP- 204

  Fly   127 VETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQY 191
            :..|.:.:.....||.|||||.|.|:|..|..|..|:.:|:...|::..::|||:.|.|||:|:.
Mouse   205 MTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLED 269

  Fly   192 FPMDRQLCHIEIESFGYTMRDIRYFW-RDGLSSVGMSSE-VELPQFRVLGHRQRATEINLTTGNY 254
            ||||...|.::..|:.||..::.|.| |:...||.::.: ..|.|:.:||....:..:..:||.|
Mouse   270 FPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEY 334

  Fly   255 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNA 319
            ..:.......|.:||::||.|:|..:.||:|.|||||||.:.|||...|||||||||||..|...
Mouse   335 VVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARN 399

  Fly   320 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQ 384
            :|||::|..::|.::..|:..||::|:|:|||.|..||
Mouse   400 SLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR--------------------------- 437

  Fly   385 QQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVS 449
                                                                  |:....|..|.
Mouse   438 ------------------------------------------------------GYAWDGKSVVP 448

  Fly   450 NRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQG 514
            .:|                          .||.||.. .|..|...|..       |:.|...:
Mouse   449 EKP--------------------------KKVKDPLI-KKNNTYAPTAT-------SYTPNLAR- 478

  Fly   515 GGPPGGGGGGGGGGGPPEGGGDPEAAVPAH--LLHPGKVK---KVKDINKLLGITPSDIDKYSRI 574
                                |||..|..|.  .:.|.:||   |..:..|... :.|.||:.|||
Mouse   479 --------------------GDPGLATIAKSATIEPKEVKPETKPPEPKKTFN-SVSKIDRLSRI 522

  Fly   575 VFPVCFVCFNLMYWIIYLH 593
            .||:.|..|||:||..||:
Mouse   523 AFPLLFGIFNLVYWATYLN 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	61/184 (33%)
		Neur_chan_memb	274..588	CDD:397193	78/318 (25%)
Gabra1	XP_006532258.1	LIC	105..539	CDD:273305	155/535 (29%)
		LGIC_ECD_GABAAR_A1	153..346	CDD:349835	65/194 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910