Protein Alignment Rdl and Gabra4

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_542154.3
• Gene: Gabra4 / 140675
• RGDID: 621670
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 627
• Identity: 193/627 - (30%)
• Similarity: 278/627 - (44%)
• Gaps: 133/627 - (21%)

  Fly    12 MAPLPRTPLLTIWLAINMALIAQETGHKRIHTVQAAT------GGGS---MLGDVNISAILDSFS 67
            |..:.:.|.:.:...:::||         :|.:..||      |..|   .|...|.:.||||..
  Rat     1 MVSVQKVPAIVLCSGVSLAL---------LHVLCLATCLNESPGQNSKDEKLCPENFTRILDSLL 56

  Fly    68 VSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSV 132
            ..||.|:||.:|||..||...:||.|...:|:|:|::|:|.:|||.|.|.||.| ..| :|.|.:
  Rat    57 DGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKY-DGP-IEILRL 119

  Fly   133 GSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQ 197
            .:..:..:|.|||||.|.|:|..|..|..|:..|:..:|:|..::||||:|.|||.|..||||..
  Rat   120 NNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGH 184

  Fly   198 LCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELP-------QFRVLGHRQRATEINLTTGNYS 255
            .|.::..|:.|...::.|.|     :.|....||:|       |:.::|....:..|...||.|.
  Rat   185 ACPLKFGSYAYPKSEMIYTW-----TKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYI 244

  Fly   256 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAA 320
            .:.......|.|||::||.|||..:.||:|.||||:|:.:.|||...|:|||||||||..|...:
  Rat   245 VMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHS 309

  Fly   321 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAE-----------Q 374
            |||:||..::|.::..||..||::|:|:|.|.|.. .|||:|    |.:||::           :
  Rat   310 LPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT-NIQMQK----AKKKISKPPPEVPAAPVLK 369

  Fly   375 KKQQLDGANQQQANPN----PNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHA 435
            :|..........||.|    .||.|.....|          .....||         .|.....|
  Rat   370 EKHTETSLQNTHANLNMRKRTNALVHSESDV----------NSRTEVG---------NHSSKTTA 415

  Fly   436 HSHGHPHAPKQTVSNRPIGFS--NIQQNV--GTRGCSIV-----------GPLFQEVRFKVHDPK 485
            ........||..:::.|..||  |..:.:  ..||.|..           .||    |.....|.
  Rat   416 AQESSETTPKAHLASSPNPFSRANAAETISAAARGLSSAASPSPHGTLQPAPL----RSASARPA 476

  Fly   486 AHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGK 550
            ..::.|.::.||| ..|.|.:....|.....||.|.|
  Rat   477 FGARLGRIKTTVN-TTGVPGNVSATPPPSAPPPSGSG---------------------------- 512

  Fly   551 VKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYL 592
                          .|.||||:||:|||.|..||::||::||
  Rat   513 --------------TSKIDKYARILFPVTFGAFNMVYWVVYL 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	64/189 (34%)
		Neur_chan_memb	274..588	CDD:397193	96/343 (28%)
Gabra4	NP_542154.3	LIC	13..539	CDD:273305	189/612 (31%)
		Neur_chan_LBD	49..256	CDD:280998	77/213 (36%)
		Neur_chan_memb	263..536	CDD:280999	96/343 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..436		17/101 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..470		5/25 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	486..513		10/69 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910