Protein Alignment Rdl and Glra3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_063131053.1
• Gene: Glra3 / 114516
• RGDID: 621229
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 575
• Identity: 176/575 - (30%)
• Similarity: 266/575 - (46%)
• Gaps: 167/575 - (29%)

  Fly    26 AINMALIA-QETGHKRIHTVQAATGGGSMLGDVNISAILDSF---SVSYDKRVRPNYGGPPVEVG 86
            |:.::|:| :||...|           |....::.|..||..   :..||.|:|||:.||||.|.
  Rat    36 ALLLSLVATKETNSAR-----------SRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 89

  Fly    87 VTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEK 151
            ..:::.|..|::|..||:.::.:.||.|.||||||.:.|. ::|.:....:.:||.||.||.|||
  Rat    90 CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD-DSLDLDPSMLDSIWKPDLFFANEK 153

  Fly   152 QSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYF 216
            .:.||..||.|:.:|:..:|::..|||||:|.||||:|:.||||.|.|.:::|||||||.|:.:.
  Rat   154 GANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFE 218

  Fly   217 WRDGLSSVGMSSEVELPQFRVLGHRQ-RATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL 280
            |:|. :.|.::..:.||||.:...:. |....:..||.::.:.......|.|||||||:||||.|
  Rat   219 WQDE-APVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLL 282

  Fly   281 IVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASL 345
            |||:||||||:|.:|.|||||||:||||||||..|.:.|:|||:||||:||:::..|.:.||::|
  Rat   283 IVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 347

  Fly   346 LEYATVGYMAKR----IQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPG 406
            ||||.|.:::::    ::.|::|           |.:.|...:.:.:
  Rat   348 LEYAAVNFVSRQHKELLRFRRKR-----------KNKDDEVRESRFS------------------ 383

  Fly   407 GPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVG 471
                       ....||||                                         |
  Rat   384 -----------FTAYGMGP-----------------------------------------C---- 392

  Fly   472 PLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGD 536
                          ..:|.|.:                                     |:|...
  Rat   393 --------------LQAKDGVV-------------------------------------PKGPNH 406

  Fly   537 PEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591
            ....:|         |...::.|:.......||..||..||:.|:.||:.||:||
  Rat   407 AVQVMP---------KSADEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	69/183 (38%)
		Cys-loop	185..199	CDD:349809	9/13 (69%)
		Neur_chan_memb	274..588	CDD:460753	76/317 (24%)
Glra3	XP_063131053.1	None