Protein Alignment Rdl and Glra3

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_536686.3
• Gene: Glra3 / 110304
• MGIID: 95749
• Length: 464
• Species: Mus musculus
• Alignment Length: 578
• Identity: 183/578 - (31%)
• Similarity: 275/578 - (47%)
• Gaps: 158/578 - (27%)

  Fly    26 AINMALIA-QETGHKRIHTVQAATGGGSMLGDVNISAILDSF---SVSYDKRVRPNYGGPPVEVG 86
            |:.::|:| :||...|           |....::.|..||..   :..||.|:|||:.||||.|.
Mouse    20 ALLLSLVATKETNSAR-----------SRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73

  Fly    87 VTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEK 151
            ..:::.|..|::|..||:.::.:.||.|.||||||.:.|. ::|.:....:.:||.||.||.|||
Mouse    74 CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD-DSLDLDPSMLDSIWKPDLFFANEK 137

  Fly   152 QSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYF 216
            .:.||..||.|:.:|:..:|::..|||||:|.||||:|:.||||.|.|.:::|||||||.|:.:.
Mouse   138 GANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFE 202

  Fly   217 WRDGLSSVGMSSEVELPQFRVLGHRQ-RATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL 280
            |:|. :.|.::..:.||||.:...:. |....:..||.::.:.......|.|||||||:||||.|
Mouse   203 WQDE-APVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLL 266

  Fly   281 IVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASL 345
            |||:||||||:|.:|.|||||||:||||||||..|.:.|:|||:||||:||:::..|.:.||::|
Mouse   267 IVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 331

  Fly   346 LEYATVGYMAKR----IQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPG 406
            ||||.|.:::::    ::.|::|....:..|.:|..:
Mouse   332 LEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYR---------------------------- 368

  Fly   407 GPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVG 471
                                                            ||:....|
Mouse   369 ------------------------------------------------FSDTDDEV--------- 376

  Fly   472 PLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGP---GQGGGPPGGGGGGGGGGGPPEG 533
               :|.||..                       .::|.||   .:.|..|.|
Mouse   377 ---RESRFSF-----------------------TAYGMGPCLQAKDGVVPKG------------- 402

  Fly   534 GGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591
               |..||......|.:::|| .|::     ...||..||..||:.|:.||:.||:||
Mouse   403 ---PNHAVQVMPKSPDEMRKV-FIDR-----AKKIDTISRACFPLAFLIFNIFYWVIY 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	69/183 (38%)
		Neur_chan_memb	274..588	CDD:397193	83/320 (26%)
Glra3	NP_536686.3	LIC	12..451	CDD:273305	181/576 (31%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O75311	235..240		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2310
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X271
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860