Protein Alignment Rdl and glra3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_002933371.1
• Gene: glra3 / 100488938
• XenbaseID: XB-GENE-1011160
• Length: 449
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 182/576 - (31%)
• Similarity: 268/576 - (46%)
• Gaps: 169/576 - (29%)

  Fly    26 AINMALIA-QETGHKRIHTVQAATGGGSMLGDVNISAILDSF---SVSYDKRVRPNYGGPPVEVG 86
            |:.::|:| :||...|           |....::.|..||..   :..||.|:|||:.||||.|.
 Frog    20 ALLLSLVATKETDSAR-----------SRPSPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73

  Fly    87 VTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEK 151
            ..::|.|..|::|..||:.|:.:.||.|.||||||.:.|. ::|.:....:.:||.||.||.|||
 Frog    74 CNIFVNSFGSIAETTMDYRLNIFLRQKWNDPRLAYSEYPD-DSLDLDPSMLDSIWKPDLFFANEK 137

  Fly   152 QSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYF 216
            .:.||..||.|:.:|:...|::..|||||:|.||||:|:.||||.|.|.:::|||||||.|:.:.
 Frog   138 GANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFE 202

  Fly   217 WRDGLSSVGMSSEVELPQFRVLGHRQ--RATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSG 279
            |::. ..|.::..:.|||| ||...:  |....:..||.::.:.......|.|||||||:||||.
 Frog   203 WQEN-GPVQIADGLTLPQF-VLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSL 265

  Fly   280 LIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFAS 344
            ||||:||||||:|.:|.|||||||:||||||||..|.:.|:|||:||||:||:::..|.:.||::
 Frog   266 LIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSA 330

  Fly   345 LLEYATVGYMAKR----IQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGP 405
            |||||.|.:::::    ::.|::|          ||.:.|...:.:.:
 Frog   331 LLEYAAVNFVSRQHKELLRFRRKR----------KKDRDDDVRESRFS----------------- 368

  Fly   406 GGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIV 470
                        ....||||                               .:|...|.
 Frog   369 ------------FTAYGMGP-------------------------------CLQAKDGV------ 384

  Fly   471 GPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGG 535
                        :||                 ||.:..|.|
 Frog   385 ------------NPK-----------------GPLNAPPAP------------------------ 396

  Fly   536 DPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591
                            |..:::.|:.......||..||..||:.|:.||:.||:||
 Frog   397 ----------------KTHEEMRKVFIDRAKKIDTLSRACFPLAFLIFNIFYWVIY 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	72/184 (39%)
		Cys-loop	185..199	CDD:349809	9/13 (69%)
		Neur_chan_memb	274..588	CDD:460753	79/317 (25%)
glra3	XP_002933371.1	LIC	12..436	CDD:273305	180/574 (31%)