Protein Alignment Rdl and gabrd

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_017951272.2
• Gene: gabrd / 100488161
• XenbaseID: XB-GENE-988598
• Length: 450
• Species: Xenopus tropicalis
• Alignment Length: 574
• Identity: 175/574 - (30%)
• Similarity: 254/574 - (44%)
• Gaps: 153/574 - (26%)

  Fly    31 LIAQETGHKRIHTVQAATGGGSMLG-DVNISAI--LDSFSVSYDKRVRPNYGGPPVEVGVTMYVL 92
            |..::.||        :...|..:| ::.||.:  ||.....|.:..||..||.||.|.|.:.|.
 Frog    15 LALEDRGH--------SEDIGEFIGSNIEISWVPNLDDLMKGYARNFRPGIGGAPVIVAVDVEVT 71

  Fly    93 SISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHI 157
            ||..:|||.|::|:..:..|.|.|.||:|....  :||.:.|.|::.:|:||||.||.|.::||.
 Frog    72 SIDHISEVNMEYTMTVFLHQSWRDERLSYNHTN--KTLGLDSRFVEKLWLPDTFIVNAKSAWFHD 134

  Fly   158 ATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLS 222
            .|..|:.||:...|.|..|.|:|.|.||.|:|..:|||.|.|.:|:||:||:..||.|.|.:...
 Frog   135 VTVENKLIRLQPDGVILYSSRITSTVSCDMDLTKYPMDEQECMLELESYGYSSEDILYRWSENQE 199

  Fly   223 SVGMSSEVELPQFRVLGHRQRATEINL-TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISW 286
            ......::||.||.|..:|....|:.| :.|.:.||:......|:.|.|:|:.|:||.|:|.:||
 Frog   200 KNHGLDKIELAQFTVTNYRFTKNEMILKSAGEFPRLSLHFHLRRNRGVYIIESYVPSILLVAMSW 264

  Fly   287 VSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATV 351
            ||||:::.|.||||:||:||||||||||.|...:||:.|.||::|||...|:|.|||:|:|||..
 Frog   265 VSFWISQAAVPARVSLGITTVLTMTTLMVSARTSLPRASAVKALDVYFLICYVFVFAALVEYAFA 329

  Fly   352 GYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVN 416
            .|.|..|:..|     ::..|.:|.:|:      |.|....|.|                  .::
 Frog   330 HYSADYIKKEK-----VKTKASKKNKQV------QMNEGQYAIV------------------LLS 365

  Fly   417 VGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFK- 480
            :.: :||.......:.||                    |:.  ||              |.|.:
 Frog   366 LSI-LGMDQSLTLINKHH--------------------FAT--QN--------------EARLEG 393

  Fly   481 --------VHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDP 537
                    ..|||
 Frog   394 MRKDKLQICRDPK---------------------------------------------------- 406

  Fly   538 EAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591
                      |.|..::|.:  |..|....||.|:|.|||..|...|::||:.|
 Frog   407 ----------PEKESRLKSL--LRPIEADSIDVYARAVFPAAFAAVNIIYWVAY 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	70/183 (38%)
		Cys-loop	185..199	CDD:349809	7/13 (54%)
		Neur_chan_memb	274..588	CDD:460753	83/322 (26%)
gabrd	XP_017951272.2	LIC	42..448	CDD:455710	167/537 (31%)
		LGIC_ECD	61..244	CDD:475126	71/184 (39%)