Protein Alignment Rdl and gabra2

DIOPT Version :9

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_002933509.2
• Gene: gabra2 / 100170583
• XenbaseID: XB-GENE-1000398
• Length: 451
• Species: Xenopus tropicalis
• Alignment Length: 574
• Identity: 163/574 - (28%)
• Similarity: 244/574 - (42%)
• Gaps: 173/574 - (30%)

  Fly    53 MLGDV-------NI---SAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLD 107
            :|||.       ||   :.|||.....||.|:||..|....||...:||.|...:|:..|::|:|
 Frog    27 VLGDTVDNDAKNNITIFTRILDRLLDGYDNRLRPGLGDRVTEVHTDIYVTSFGPVSDTDMEYTID 91

  Fly   108 FYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGS 172
            .:|||.|.|.||.: |.| :..|.:.:.....||.|||||.|.|:|..|..|..|:.:|:...|:
 Frog    92 VFFRQNWQDERLRF-KGP-MHILRLNNLMANKIWTPDTFFHNGKKSIAHNMTMPNKLLRIQDDGT 154

  Fly   173 ITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFW-RDGLSSVGMSSE-VELPQF 235
            :..::|||:.|.|||:|:.||||...|.::..|:.||..::.|.| |:...||.::.: ..|.|:
 Frog   155 LLYTMRLTVQAECPMHLEDFPMDAHACPLKFGSYAYTTSEVTYVWTRNATESVVVAPDGSRLNQY 219

  Fly   236 RVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARV 300
            .:|||......|..:||.|:.:.......|.:||::||.|:|..:.||:|.|||||||.:.|||.
 Frog   220 VLLGHLVGKETIKSSTGEYTVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 284

  Fly   301 ALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR-------- 357
            ..|||||||||||..|...:|||::|..::|.::..|:..||::|:|:|||.|..||
 Frog   285 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKS 349

  Fly   358 --IQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVG 420
              ...:|::...|:|
 Frog   350 VVNDKKKEKASVIKK-------------------------------------------------- 364

  Fly   421 MGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPK 485
                        ::|::               :..:|...|: |:..::  |..
 Frog   365 ------------NNAYA---------------VAVANYAPNI-TKDSAL--PTI----------- 388

  Fly   486 AHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGK 550
              ||..|                                          .||..|.|.
 Frog   389 --SKSAT------------------------------------------ADPNKAKPQ------- 402

  Fly   551 VKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVL 604
             :..|..|.:     |.||:.||||||:.|..|||:||..||: .::..:.|||
 Frog   403 -EAKKTFNSV-----SKIDRMSRIVFPLLFGTFNLVYWATYLN-RELAIEGLVL 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	64/184 (35%)
		Neur_chan_memb	274..588	CDD:397193	73/323 (23%)
gabra2	XP_002933509.2	LIC	12..437	CDD:273305	158/559 (28%)
		LGIC_ECD_GABAAR_A2	48..250	CDD:349836	71/203 (35%)
		Cys-loop	167..181	CDD:349836	8/13 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100