Protein Alignment Rdl and gabrb3

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001096164.1
• Gene: gabrb3 / 100124708
• XenbaseID: XB-GENE-6030743
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 183/584 - (31%)
• Similarity: 278/584 - (47%)
• Gaps: 154/584 - (26%)

  Fly    50 GGSMLGDVNISAIL----------------------DSFSVSYDKRVRPNYGGPPVEVGVTMYVL 92
            ||.:||.:::..::                      |.....||.|:||::||.||.||:.:.:.
 Frog     6 GGQLLGLISVPILISMVCSTQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGSPVAVGMNIDIA 70

  Fly    93 SISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHI 157
            ||..:|||.||:||..||:|:|.|.||||...|  ..|::.:.....:|||||:|:|:|:|:.|.
 Frog    71 SIDMVSEVNMDYTLTMYFQQYWRDKRLAYTGIP--LNLTLDNRVADQLWVPDTYFLNDKKSFVHG 133

  Fly   158 ATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLS 222
            .|..|..||:|..|::...:|:|.||:|.|:|:.:|:|.|.|.:||||:|||..||.::|..|.:
 Frog   134 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWLGGDN 198

  Fly   223 SVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWV 287
            :|.....:|||||.::.|:..:..:...||:|.||:...:..|::||:::|.|:||.||.|:|||
 Frog   199 AVTGVERIELPQFSIMDHKLVSKNVVFATGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWV 263

  Fly   288 SFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG 352
            |||:|.:|:.||||||:||||||||:.:.....||||.|||:||:||..|||.||.:|||||.|.
 Frog   264 SFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVN 328

  Fly   353 YM--AKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGV 415
            |:  .:..||:|       |:||:..:.
 Frog   329 YIFFGRGPQMQK-------KLAEKSAKS------------------------------------- 349

  Fly   416 NVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFK 480
                    ..:|.....:...:||:.......:.|...|                    .|:...
 Frog   350 --------NKDHSKFESNRVDAHGNILLTTLEIHNEVTG--------------------NEITTS 386

  Fly   481 VHDPK-----------AHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGG 534
            |.|.:           .:.|..|..::: |.|...::|                      ||:
 Frog   387 VSDARNSATSFDNSGIQYRKQSTARDSL-GRRTADRNH----------------------PPK-- 426

  Fly   535 GDPEAAVPAHLLHPGKVKKVK-----DINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 593
                   ..||.......|:|     |:|.        ||::||||||:.|..|||:||:.|::
 Frog   427 -------KTHLRRRSSQLKIKIPDLTDVNA--------IDRWSRIVFPITFSLFNLIYWLYYIN 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	73/182 (40%)
		Cys-loop	185..199	CDD:349809	6/13 (46%)
		Neur_chan_memb	274..588	CDD:460753	90/331 (27%)
gabrb3	NP_001096164.1	LIC	11..473	CDD:273305	179/575 (31%)