DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nwk and AT4G18060

DIOPT Version :9

Sequence 1:	NP_001286994.1	Gene:	nwk / 39052	FlyBaseID:	FBgn0263456	Length:	1075	Species:	Drosophila melanogaster
Sequence 2:	NP_193540.3	Gene:	AT4G18060 / 827531	AraportID:	AT4G18060	Length:	351	Species:	Arabidopsis thaliana

Alignment Length:	478	Identity:	94/478 - (19%)
Similarity:	154/478 - (32%)	Gaps:	171/478 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 ATQNSFGKIRDQA--QQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETL- 330
            |.:....|:|||.  |||.             |:||.....:|:.|...:.::..:.....:.|
plant     3 AFRRQASKLRDQVAKQQLA-------------VIKQFSGTGYESSDVMVIDELEMQRHHQLDKLY 54

  Fly   331 --TKEAKNLAGRVVKENASIR-------ENAKKLA--LCQSLRDSGQRTDPN----------DPN 374
              |:.||.....:||...:..       |...||:  .|:...::.|..|.|          |..
plant    55 RSTRSAKEFQRDIVKAAEAFTTIGLRHIEAGTKLSEDCCRYGNENSQNIDENILAKAAAIYGDAR 119

  Fly   375 GPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEAENMGVQELTRSASSISMRT 439
             ..:|.:.|:|         .|..|...|..||  .:.....:::|.:: .|..:|      ||.
plant   120 -KHVDKEQEDF---------NKLLASQVLDPLR--AMVAGSPLEDARHL-AQRYSR------MRQ 165

  Fly   440 DASGQGENPSSDSFYDSDKEETQAAAQTKPKQEQQLSRDRTFSDSEDEPEVRPSAAAASSAAAAS 504
            :|                  ||.|   |:..:.|...|         |..:..:.|....|.|..
plant   166 EA------------------ETHA---TEVSRRQARVR---------EAPIPENVAKLQLAEAKM 200

  Fly   505 SSMMASSA--GGWDDPTEVNWGAGEEEDDKDEPIVPEPKEAIFKCTALYSYTAQNPDELTIVENE 567
            ..:.|:.|  |                           |||    ||..:........||.   :
plant   201 QELKANMAVLG---------------------------KEA----TAALAAVESQQHRLTF---Q 231

  Fly   568 QLEVVGEGDGDGWLRARNYRGEEGYVPHNYLDIDQETAGSAFNGTSGNQLRSQISFSSVDYTVDN 632
            :|..:.||:       :||                             .||.....|.::..:..
plant   232 RLVAMVEGE-------KNY-----------------------------HLRIAAILSDIEAEMVT 260

  Fly   633 EDQTVDSMQSPDQVSVIMAPQKRVKSDVEWCIA--LYDYDATAEDELTFEEGDKIKIITKTAHGV 695
            |.|..:|  :|..:     |.:.......:.:|  ::.:.|.:|.||..::||.| ::.|.:
plant   261 EKQHKES--APPAI-----PTENGSEKTSYFLAEVIHPFSAASEKELDLDKGDYI-VVRKVS--- 314

  Fly   696 DDGWWEGELDGKFGNFPSLVVEE 718
            ..||.|||..||.|.||...:|:
plant   315 QTGWAEGECKGKAGWFPMAYIEK 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nwk	NP_001286994.1	BAR	16..281	CDD:353336	4/11 (36%)
		SH3_FCHSD_1	545..600	CDD:212695	9/54 (17%)
		SH3	663..718	CDD:354299	19/56 (34%)
		PRK12323	<725..956	CDD:237057
AT4G18060	NP_193540.3	BAR	49..257	CDD:416402	56/326 (17%)
AT4G18060	NP_193540.3	SH3	285..337	CDD:418401	19/55 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000