Protein Alignment nwk and toca-1

DIOPT Version :9

• Sequence 1: NP_001286994.1
• Gene: nwk / 39052
• FlyBaseID: FBgn0263456
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_741723.1
• Gene: toca-1 / 180492
• WormBaseID: WBGene00017298
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 666
• Identity: 134/666 - (20%)
• Similarity: 234/666 - (35%)
• Gaps: 204/666 - (30%)

  Fly    34 DLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKKIPNIPDIKMEGMEERWNMWSVWR------- 91
            ||||.|..::.:|:::|..||..|     :.|:||..    :||:...|.||..|..:
 Worm    26 DLLERIMAYSKERASIELEYSSKL-----KALSKKTA----MKMKSESELWNSVSYVKGFHDVIA 81

  Fly    92 ---TVLEENEKLA-RARLAAIEVFQQQIADEAKVLRDYKLAIAKRSL-AGIVNVQKELHLSVGDV 151
               .|..::|.:| ..:.|.|....|:||       :|:  :||:.| :...|:.|:|.:.:.::
 Worm    82 GIVPVATQHELIAENLKSAVIPFTTQKIA-------EYR--VAKKQLESDNSNLGKQLRMVIDEM 137

  Fly   152 DKTKKSY---FDEEHCA---HDVRDKARDIEE-KLKKKKGSFFQSITSLQKNSARVTSRKELLEE 209
            .|:.|.|   :.|...|   :...:|..||.. :|:|.|.::.|              :..:|||
 Worm   138 AKSHKEYVKCYKETEAAMLKYAKAEKNMDISRLELEKTKNNYQQ--------------KCGMLEE 188

  Fly   210 KSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNSF 274
                ::..|.:....||..|:.::...|.   ..::||              .:|.|
 Worm   189 ----SKQTYAVMTTKANEEQSAHYDRKLP---QLLDNY--------------KKLHT-------- 224

  Fly   275 GKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKE------ 333
            .:|.|..:.|::....:.|          :.....:|.||..|.:.....|....|..|
 Worm   225 NRILDTVEILSKCVEAESC----------VNQIIASCHNDMRRDIGLIDPSRDANLVVENMKSGH 279

  Fly   334 ------------------------AKNLAGRVVKENASIR-------ENAKKLALCQSLRD---- 363
                                    |...||.:...:|:::       :|.|.:|..||:..
 Worm   280 PVPQPFVFEDLGHPQDRSSFMGGGASGPAGSMDGMDATMKKGGTLMSKNGKGVARKQSMHQKFFG 344

  Fly   364 ---SGQRTDPNDPNGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEAENMGV 425
               :.::||..|........:..:...:|...|.||.:|
 Worm   345 GGTADKKTDSGDYGTLPPQQRARKIAGKISDLEKEKDRA-------------------------- 383

  Fly   426 QELTRSASSISMRTDASGQGENPSSDSFYDSDKEETQAAAQTKPKQEQ-------------QLSR 477
               |:|...:|....|  ..|||...:..|.|.:..|...:......|             ||..
 Worm   384 ---TQSREGVSKMQAA--YRENPKLGNPSDCDAQLAQYGHEIDALSNQIQKFKILLDDVNAQLGA 443

  Fly   478 DRTFSDSEDEPEVRPSAAAASSAAAASSSMM---------------------ASSAGGWD-DPTE 520
            ....:.|....:..||..:.|||::..:|.:                     :.|.||.| |||
 Worm   444 GGLSATSVGGSDTPPSIRSVSSASSGVTSRVNTINDAHRTNGGVGGGRRESFSGSNGGSDTDPT- 507

  Fly   521 VNWGAGEEEDDKDEPIVPEPKEAIFKCTALYSYTAQNPDELTIVENEQLEVVGEGDGDGWLRARN 585
            :| |.|...|:..|. ...|...:.:..|.:::.......:.:..||:|.::.:.:||||.|.|.
 Worm   508 IN-GNGHGRDELYEE-CSNPNPVLGEAIAQFAFDGAQDGTIRMEANEKLWLIEKDEGDGWTRVRK 570

  Fly   586 YRGE-EGYVPHNYLDI 600
            .... :|:||.:||.:
 Worm   571 ENNSADGFVPSSYLKV 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nwk	NP_001286994.1	BAR	16..281	CDD:353336	60/265 (23%)
		SH3_FCHSD_1	545..600	CDD:212695	15/55 (27%)
		SH3	663..718	CDD:354299
		PRK12323	<725..956	CDD:237057
toca-1	NP_741723.1	F-BAR_CIP4-like	8..259	CDD:153337	66/303 (22%)
		HR1_CIP4-like	362..438	CDD:212009	16/106 (15%)
		SH3_CIP4-like	532..586	CDD:212844	15/53 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D348563at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010