Protein Alignment nwk and fchsd2

DIOPT Version :9

• Sequence 1: NP_001286994.1
• Gene: nwk / 39052
• FlyBaseID: FBgn0263456
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: XP_031751437.1
• Gene: fchsd2 / 100124657
• XenbaseID: XB-GENE-5824265
• Length: 784
• Species: Xenopus tropicalis
• Alignment Length: 872
• Identity: 278/872 - (31%)
• Similarity: 428/872 - (49%)
• Gaps: 191/872 - (21%)

  Fly     1 MQPPPRKGNYVKFLKNLHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYL 65
            |||||||....:.|||:|:||:.|||.|:|.|||||||:|.|:.|::|||:.|::::.|::||||
 Frog    11 MQPPPRKVKVTQELKNIHSEQMTKLQAKHQAECDLLEDMRTFSQKKAAVEREYAQTIQKLASQYL 75

  Fly    66 NKKIPNI-PDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAI 129
            .|:.|.: ||   |..|.| ::::||::.||...::.::::...|.::..|::.|:.::.||...
 Frog    76 KKEWPAVKPD---ERSEYR-SIYTVWKSFLEGTMQVTQSQINICENYKNLISEPARTVKLYKEQQ 136

  Fly   130 AKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQ 194
            .||.:..:..:|.||..:|.|:.|.||.|::.|..||.:|:|| ||:   .|.|.|.|||..|||
 Frog   137 LKRCVDQLTKIQAELQETVKDLAKAKKKYYEAEQMAHAMREKA-DID---AKSKLSLFQSRISLQ 197

  Fly   195 KNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLM 259
            |.:.::.:|:.....|::.|||||:|:||||||||:||:..||...|..::..|::.:.:|||.:
 Frog   198 KANVKLKARRSECNAKATHARNDYLLTLAAANAHQDRYYQTDLANAMKALDGNVYDHLKDYLMAL 262

  Fly   260 GRTELLTCSATQNSFGKIRDQAQQ----------LTREYNLQCCYLFYPVLKQHIQYDFEACDND 314
            .||||..|.|.||:|..:.:.:.:          :.|:||||.......|..:...:.|:.||:|
 Frog   263 SRTELEKCQAVQNTFQYLLETSSRAFMQLKFPSSVMRDYNLQLFVQENLVFHKAQPFQFQPCDSD 327

  Fly   315 --------------PV----------RKVTAEHESAAE-TLTKEAKNLAGRVVKENASIRENAKK 354
                          ||          |::.:|..:..| :|.|||:..|.||.:|:.:|..:.:.
 Frog   328 TSFSAVPLVDIEPSPVSAMRMILAKSRQLESETGTTEEHSLNKEARKWATRVAREHKNIIHSQRA 392

  Fly   355 LALCQSLRDSGQRTDPNDPNGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQE 419
            |...:.     |.|..::.:..:|:.||||.|:.:|::|..|.||||.|..||..|::||.|::.
 Frog   393 LEELEC-----QTTPVSEQSRMELEQKIEETRENMRKAEITKLKAEARLDLLRQIGVSVDTWLKS 452

  Fly   420 AENMGVQEL--TRSASSISMRTDASGQGENPSSDSFYDSDKEETQAAAQTKPKQEQQLSRDRTFS 482
            |.|..::||  .|.||..::..:.|      |.....|.|:|:         .:|.:.|.| .|.
 Frog   453 AMNQVMEELENERWASLPTLMNNGS------SHMGGTDVDRED---------GEELEDSMD-AFD 501

  Fly   483 DSEDEPEVRPSAAAASSAAAASSSMMASSAGGWDDPTEVNWGAGEEEDDKDEPIVPEPKEAIFKC 547
            ||...|               |.::                        ::.|:.         |
 Frog   502 DSSSSP---------------SGTL------------------------RNYPLT---------C 518

  Fly   548 TALYSYTAQNPDELTIVENEQLEVVGEGDGDGWLRARNYRGEEGYVPHNYLDIDQETAGSAFNGT 612
            ..:|||.|..||||||.|:|.|||:.:||.:.|::|||..|:.||||..||..           .
 Frog   519 KVIYSYKASQPDELTIEEHEMLEVIEDGDMEDWVKARNKSGQVGYVPEKYLQF-----------P 572

  Fly   613 SGNQLRSQISFSSVDYTVDNEDQTVDSMQSPDQVSVIMAPQKRVKSDVEWCI--ALYDYDATAED 675
            :.|.|.|.:...:   .:|:...|..:....|..|      ..:..|...|.  |||:||...:|
 Frog   573 ASNSLLSMLQSLA---ALDSRSHTSSNSNDADMAS------GSLNGDTNVCFVKALYEYDGQTDD 628

  Fly   676 ELTFEEGDKIKIITKTAHGVDDGWWEGELDGKFGNFPSLVVEECDEMGEPLSEGGDE-------- 732
            ||:|.||..|:|:.|.... |||:||||.:|:.|.|||::|||...     ||.||.
 Frog   629 ELSFPEGAIIRILNKENQD-DDGFWEGEFNGRIGVFPSVLVEELTG-----SENGDAQWFGDVQI 687

  Fly   733 SPPPTAAPTFALPPAPAL--PPE---YAHELELELTEDMFGSQDTADEDSGYIPNGAAAPSIPPP 792
            ||.|  .|..:|||.|..  ||.   |:.:                ..::.|.|.   :||
 Frog   688 SPSP--KPQNSLPPLPLYDQPPSSPLYSPD----------------KNNAQYFPR---SPS---- 727

  Fly   793 VLIQEPGMEDDLSDD----GQPPPSLP 815
                  |.|:::|.|    ..||.|:|
 Frog   728 ------GNENNMSLDSPGTSHPPRSMP 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nwk	NP_001286994.1	BAR	16..281	CDD:353336	107/265 (40%)
		SH3_FCHSD_1	545..600	CDD:212695	29/54 (54%)
		SH3	663..718	CDD:354299	28/56 (50%)
		PRK12323	<725..956	CDD:237057	27/108 (25%)
fchsd2	XP_031751437.1	F-BAR_FCHSD2	26..285	CDD:153361	107/266 (40%)
		SH3_FCHSD_1	515..571	CDD:212695	30/64 (47%)
		SH3_FCHSD2_2	615..670	CDD:212827	27/55 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	179	1.000	Domainoid score	I3471
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8887
Inparanoid	1	1.050	362	1.000	Inparanoid score	I2146
OMA	1	1.010	-	-		QHG52870
OrthoDB	1	1.010	-	-		D154524at33208
OrthoFinder	1	1.000	-	-		FOG0007087
OrthoInspector	1	1.000	-	-		otm47629
Panther	1	1.100	-	-	O	PTHR15735
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2901
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080