Protein Alignment Use1 and USE1

DIOPT Version :9

• Sequence 1: NP_648289.2
• Gene: Use1 / 39051
• FlyBaseID: FBgn0035965
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_060937.2
• Gene: USE1 / 55850
• HGNCID: 30882
• Length: 259
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 82/263 - (31%)
• Similarity: 135/263 - (51%)
• Gaps: 21/263 - (7%)

  Fly     2 ATKLNVNIRTLLANCEELA--KSEQNFWRLQKFIKSLDTMLAELEAMGDPQSVKRIPGYLER--- 61
            |::|.:|:..||:.||.:|  |.:.:.|||:|::.:|:.||..|:......:.:.|..|..:
Human     3 ASRLELNLVRLLSRCEAMAAEKRDPDEWRLEKYVGALEDMLQALKVHASKPASEVINEYSWKVDF 67

  Fly    62 ----LQALKISTGYADVPGSTTKTPSQSSAVSETGENALKEIRQLQNSKYHNELRKELLQDSDA- 121
                |||.|:::.......:....|.:....:.....|.|.:.....::|.:|:|.|||....|
Human    68 LKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGTDSAE 132

  Fly   122 ----LRRRRGADESSSSSGSANVQETS-GENMNQAAKYYTNAQEKITEHMLSLTRNLKEQTETAN 181
                :|:|.|.      :||..|.|.. ...::...:.:.|.|||:.|.||.|.|:||..|..|.
Human   133 PEMDVRKRTGV------AGSQPVSEKQLAAELDLVLQRHQNLQEKLAEEMLGLARSLKTNTLAAQ 191

  Fly   182 RIIRRDTEVVSRSAGMADRNINSLGKEAEKLEQHSKKAYKCWLWLMIAFVIATFIGMVLFMKIMK 246
            .:|::|.:.:|.|..|||:|:..|..|:|:||||::|:....||.|:..|...||.|:||::||.
Human   192 SVIKKDNQTLSHSLKMADQNLEKLKTESERLEQHTQKSVNWLLWAMLIIVCFIFISMILFIRIMP 256

  Fly   247 KKK 249
            |.|
Human   257 KLK 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Use1	NP_648289.2	Use1	5..245	CDD:286796	77/254 (30%)
USE1	NP_060937.2	Use1	6..255	CDD:313048	77/254 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149509
Domainoid	1	1.000	121	1.000	Domainoid score	I5704
eggNOG	1	0.900	-	-		E1_KOG2678
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10214
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4718
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48592
OrthoDB	1	1.010	-	-		D1442410at2759
OrthoFinder	1	1.000	-	-		FOG0005428
OrthoInspector	1	1.000	-	-		oto90839
orthoMCL	1	0.900	-	-		OOG6_104533
Panther	1	1.100	-	-	LDO	PTHR13050
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2891
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800