DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Use1 and use1

DIOPT Version :9

Sequence 1:	NP_648289.2	Gene:	Use1 / 39051	FlyBaseID:	FBgn0035965	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_956618.1	Gene:	use1 / 393294	ZFINID:	ZDB-GENE-040426-1015	Length:	258	Species:	Danio rerio

Alignment Length:	267	Identity:	80/267 - (29%)
Similarity:	134/267 - (50%)	Gaps:	31/267 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAT-KLNVNIRTLLANCEELA--KSEQNFWRLQKFIKSLDTMLAELEAMGDPQSVKRIPGYLERL 62
            ||| :|.:|...||:.||.||  |..:..|||:|::.:|:.|...|:......:.:.:..|..::
Zfish     1 MATSRLEINFVRLLSRCESLASEKRAETEWRLEKYVGALEEMFVALKKSPSKPTPETLTDYNRKV 65

  Fly    63 QALKISTGYADVPGSTTKT-------PSQSSAVSETGENALKEIRQLQNSKYHNELRKELLQD-- 118
            ..||.......:|....|:       |.::..:|.....|.|.:.....::...|:||||:..
Zfish    66 DFLKGLLEAEKLPSPAEKSLANQFLAPGRTPTISSERTPASKTVHIQSKARCAGEMRKELMSSGV 130

  Fly   119 ------SDALRRRRG--ADESSSSSGSANVQETSGENMNQAAKYYTNAQEKITEHMLSLTRNLKE 175
                  .:.||.|:.  .||..|::           .::|..:::.|.|||:.:.||:|.||||.
Zfish   131 SNSALLENDLRHRKSLPVDERQSAA-----------ELDQILQHHHNLQEKLADDMLNLARNLKN 184

  Fly   176 QTETANRIIRRDTEVVSRSAGMADRNINSLGKEAEKLEQHSKKAYKCWLWLMIAFVIATFIGMVL 240
            .|..|..||::|.:.:::|...||.|...|..|:|:||||:||:...:||||:..|..|||.|:|
Zfish   185 NTLAAQNIIKQDNQTLTQSMRQADVNFEKLKTESERLEQHAKKSVNWFLWLMLIVVSFTFISMIL 249

  Fly   241 FMKIMKK 247
            |:::..:
Zfish   250 FIRLFPR 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Use1	NP_648289.2	Use1	5..245	CDD:286796	77/258 (30%)
use1	NP_956618.1	Use1	6..254	CDD:286796	77/258 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583647
Domainoid	1	1.000	121	1.000	Domainoid score	I5661
eggNOG	1	0.900	-	-		E1_KOG2678
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10214
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4723
OMA	1	1.010	-	-		QHG48592
OrthoDB	1	1.010	-	-		D1442410at2759
OrthoFinder	1	1.000	-	-		FOG0005428
OrthoInspector	1	1.000	-	-		oto40257
orthoMCL	1	0.900	-	-		OOG6_104533
Panther	1	1.100	-	-	LDO	PTHR13050
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2891
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800