DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhpr and qdpra

DIOPT Version :9

Sequence 1:	NP_001014579.1	Gene:	Dhpr / 39050	FlyBaseID:	FBgn0035964	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001103939.1	Gene:	qdpra / 566323	ZFINID:	ZDB-GENE-070705-197	Length:	237	Species:	Danio rerio

Alignment Length:	235	Identity:	138/235 - (58%)
Similarity:	178/235 - (75%)	Gaps:	1/235 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAGRVVIYGGKGALGSACVDHFKANNYWVGSIDLTENEKADVSIVVPRDASWVEQEETVVSKVGE 66
            :|.||::||||||||||||.:||:..:||.|||:..||:|:.:::|....|:.:|...|.|.|.:
Zfish     3 AANRVLVYGGKGALGSACVHYFKSKGWWVASIDIGANEEANANVLVKLSESFTDQAAQVTSDVSK 67

  Fly    67 SLAGEKLDAVICVAGGWAGGN-AKKDLAKNADLMWKQSVLTSAISAAVAAQHLKAGGLLALTGAK 130
            .|...|::|::|||||||||| :.|||.||:|:||||||.||.||:.:|:.|||.||||.|.|||
Zfish    68 LLGEHKVEAIVCVAGGWAGGNCSSKDLYKNSDMMWKQSVWTSTISSHLASLHLKPGGLLTLAGAK 132

  Fly   131 PALEGTPGMIGYGMAKAAVHQLTRSLGAEKSGLPAGSLAVSILPVTLDTPMNRKWMPDADFGTWT 195
            .:|:.||||:||||||||||||.:||..|.||||:|::||:|||||||||||||:|||||||:||
Zfish   133 ASLDATPGMVGYGMAKAAVHQLCKSLAGENSGLPSGAVAVAILPVTLDTPMNRKFMPDADFGSWT 197

  Fly   196 PLTEVAGLFLKWTQDQERPKTGSLLQLITTNGITQLIAAE 235
            ||..:|..|..|.....||.:|||:||.||.|.|:..|.:
Zfish   198 PLEYIAETFHSWATGSGRPASGSLIQLETTGGKTEATAVQ 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhpr	NP_001014579.1	DHPR_SDR_c_like	3..224	CDD:187595	133/221 (60%)
Dhpr	NP_001014579.1	adh_short	6..188	CDD:278532	111/182 (61%)
qdpra	NP_001103939.1	DHPR_SDR_c_like	4..226	CDD:187595	133/221 (60%)
qdpra	NP_001103939.1	PRK12828	7..222	CDD:237220	128/214 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586788
Domainoid	1	1.000	231	1.000	Domainoid score	I2364
eggNOG	1	0.900	-	-		E2759_KOG4022
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2824
OMA	1	1.010	-	-		QHG53721
OrthoDB	1	1.010	-	-		D1585354at2759
OrthoFinder	1	1.000	-	-		FOG0006184
OrthoInspector	1	1.000	-	-		otm24812
orthoMCL	1	0.900	-	-		OOG6_103925
Panther	1	1.100	-	-	LDO	PTHR15104
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4419
SonicParanoid	1	1.000	-	-		X2361
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800