DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhpr and qdprb.4

DIOPT Version :9

Sequence 1:	NP_001014579.1	Gene:	Dhpr / 39050	FlyBaseID:	FBgn0035964	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001104643.1	Gene:	qdprb.4 / 563255	ZFINID:	ZDB-GENE-080219-12	Length:	257	Species:	Danio rerio

Alignment Length:	226	Identity:	123/226 - (54%)
Similarity:	162/226 - (71%)	Gaps:	1/226 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVVIYGGKGALGSACVDHFKANNYWVGSIDLTENEKADVSIVVPRDASWVEQEETVVSKVGESLA 69
            :|::||||||||:..|.:|:|.::||.|:|:..|::|:.::.|....|:.:|.:.|...|.:.|.
Zfish    24 KVIVYGGKGALGTESVRYFRAKHWWVVSVDVRVNKEANANVKVKMTESFTDQAKQVTVGVSKLLG 88

  Fly    70 GEKLDAVICVAGGWAGGNAK-KDLAKNADLMWKQSVLTSAISAAVAAQHLKAGGLLALTGAKPAL 133
            .||:||:.|||||.|.|||| |.|.|.|||||||:|.||.|...:|.::|:.||||.|||||.||
Zfish    89 VEKVDAIFCVAGGQAEGNAKAKSLYKYADLMWKQNVWTSTICTHLATRYLRVGGLLTLTGAKVAL 153

  Fly   134 EGTPGMIGYGMAKAAVHQLTRSLGAEKSGLPAGSLAVSILPVTLDTPMNRKWMPDADFGTWTPLT 198
            ..|...:.:|||||:|||||||||...||||..|:|::|||||||||.|||.||:||..:||||.
Zfish   154 GPTAESVSFGMAKASVHQLTRSLGGPNSGLPPRSVALAILPVTLDTPTNRKIMPNADVSSWTPLN 218

  Fly   199 EVAGLFLKWTQDQERPKTGSLLQLITTNGIT 229
            .|..||.|||..:.||.:|||::|:||||.|
Zfish   219 HVTQLFFKWTVGKSRPPSGSLVELVTTNGKT 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhpr	NP_001014579.1	DHPR_SDR_c_like	3..224	CDD:187595	118/219 (54%)
Dhpr	NP_001014579.1	adh_short	6..188	CDD:278532	99/182 (54%)
qdprb.4	NP_001104643.1	DHPR_SDR_c_like	23..244	CDD:187595	118/219 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586787
Domainoid	1	1.000	231	1.000	Domainoid score	I2364
eggNOG	1	0.900	-	-		E2759_KOG4022
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2824
OMA	1	1.010	-	-		QHG53721
OrthoDB	1	1.010	-	-		D1585354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24812
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15104
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2361
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.870