DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bol and BOLL

DIOPT Version :9

Sequence 1:	NP_001261614.1	Gene:	bol / 39049	FlyBaseID:	FBgn0011206	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001271290.1	Gene:	BOLL / 66037	HGNCID:	14273	Length:	339	Species:	Homo sapiens

Alignment Length:	270	Identity:	90/270 - (33%)
Similarity:	130/270 - (48%)	Gaps:	59/270 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHKIAAAPPPSATPGGGLETPLAAPKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKII 65
            |...:.:|.|:......|..|.:||:|||:||||||||||...|.|:||.:.||.||:||..||:
Human     7 MQTDSLSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIV 71

  Fly    66 VDRAGVSKGYGFVTFETEQEAQRLQADGECVVLRDRKLNIAPAIKKQP--NPLQSIVATNGAVYY 128
            .||||||||||||||||:::||::..:.|.:..:|:||||.|||:||.  .|..||:...|.:|.
Human    72 NDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYL 136

  Fly   129 TTT-----------------------PPAPISNI---------PMDQFAAAVYPPVTD-FTAAGV 160
            ||:                       ||.|..::         |:.|..|..|..:.. .|...:
Human   137 TTSTGYPYTYHNGVAYFHTPEVTSVPPPWPSRSVCSSPVMVAQPIYQQPAYHYQGIKQCHTRRWM 201

  Fly   161 PAIYP-----PSAMQYQPFYQYYSVPM----NVPTIWPQNYQENHSP---------------LLH 201
            .::.|     .:..||.|....:|||.    :.|.::.|..:..:.|               |:.
Human   202 DSLLPFTKCDEATTQYLPGQWQWSVPQPSASSAPFLYLQPSEVIYQPVEIAQDGGCVPPPLSLME 266

  Fly   202 SPTSNPHSPH 211
            :....|:|.|
Human   267 TSVPEPYSDH 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bol	NP_001261614.1	RRM_DAZL_BOULE	31..111	CDD:240858	49/79 (62%)
BOLL	NP_001271290.1	RRM_BOULE	37..117	CDD:241117	49/79 (62%)
BOLL	NP_001271290.1	RRM	<38..>119	CDD:223796	49/80 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146922
Domainoid	1	1.000	77	1.000	Domainoid score	I8875
eggNOG	1	0.900	-	-		E33208_3BEMJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4535
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1610446at2759
OrthoFinder	1	1.000	-	-		FOG0002544
OrthoInspector	1	1.000	-	-		oto89569
orthoMCL	1	0.900	-	-		OOG6_107966
Panther	1	1.100	-	-	LDO	PTHR11176
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2474
SonicParanoid	1	1.000	-	-		X491
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790