Protein Alignment bol and RBM24

DIOPT Version :10

• Sequence 1: NP_001261614.1
• Gene: bol / 39049
• FlyBaseID: FBgn0011206
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_001137414.1
• Gene: RBM24 / 221662
• HGNCID: 21539
• Length: 236
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 51/217 - (23%)
• Similarity: 75/217 - (34%)
• Gaps: 78/217 - (35%)

  Fly    34 RIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDR-AGVSKGYGFVTFETEQEAQRLQADGECVV 97
            :|||||:...||:|.|.:.|..:|.::...:|.|| .|.|:||||||......|:|...|.. .:
Human    12 KIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPN-PI 75

  Fly    98 LRDRKLNI-----------------------APAIKKQP-----------------------NPL 116
            :..||.|:                       .||:.::|                       .|.
Human    76 IDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPT 140

  Fly   117 QSIVAT------NGAVY--YTTTPPAPISNIPMDQFAAAVYPPVTDFTAAG---------VPAIY 164
            .:..:|      .||.|  |:....|..:....||:..|..|....:..||         :.|..
Human   141 AAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAAGYVTAGGYGYAVQQPITAAA 205

  Fly   165 PPSAM-------------QYQP 173
            |.:|.             ||||
Human   206 PGTAAAAAAAAAAAAAFGQYQP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bol	NP_001261614.1	RRM_DAZL_BOULE	31..111	CDD:409846	30/100 (30%)
		PABP-1234	<45..219	CDD:130689	45/206 (22%)
RBM24	NP_001137414.1	RRM_RBM24_RBM38_like	11..86	CDD:409818	28/74 (38%)
		Necessary for interaction with EIF4E. /evidence=ECO:0000269|PubMed:29358667	175..199		5/23 (22%)