Protein Alignment bol and DAZ1

DIOPT Version :10

• Sequence 1: NP_001261614.1
• Gene: bol / 39049
• FlyBaseID: FBgn0011206
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_004072.3
• Gene: DAZ1 / 1617
• HGNCID: 2682
• Length: 744
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 76/282 - (26%)
• Similarity: 103/282 - (36%)
• Gaps: 94/282 - (33%)

  Fly     5 AAAPPPSATPGGGLETPLAAPKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRA 69
            |:....||....|...|     .|.::||.:|||||.....|.::...|..||:||..|||.:|.
Human   347 ASTQSSSAAASQGWVLP-----EGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRT 406

  Fly    70 GVSKGYGFVTFETEQEAQRLQADGECVVLRDRKLNIAPAIKK--------QPNPLQSIVATNGAV 126
            |||||||||:|..:.:.|::.  |..:....:||.:.|||:|        ||.||
Human   407 GVSKGYGFVSFVNDVDVQKIV--GSQIHFHGKKLKLGPAIRKQKLCARHVQPRPL---------- 459

  Fly   127 YYTTTPPAP-------------------ISNIPMDQF--AAAVYPPVTDFTAAGVPAI------- 163
              ...||.|                   |:..|:.|.  |.:.||........|...:
Human   460 --VVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEY 522

  Fly   164 --YPPSAMQ-----------YQPFYQYYSVPMNVPTIWP---QNYQENHSPLLHSPTSNPHSPHS 212
              ||.||.|           ||||..|...|..|...:.   .|||        :..:.|:||..
Human   523 PTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQ--------AFPAYPNSPFQ 579

  Fly   213 ---------------QSHPQSP 219
                           .::|.||
Human   580 VATGYQFPVYNYQPFPAYPSSP 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bol	NP_001261614.1	RRM_DAZL_BOULE	31..111	CDD:409846	34/79 (43%)
		PABP-1234	<45..219	CDD:130689	61/240 (25%)
DAZ1	NP_004072.3	RRM_DAZL	35..116	CDD:410073
		PABP-1234	42..603	CDD:130689	76/282 (27%)
		RRM_DAZL	200..281	CDD:410073
		RRM_DAZL	365..446	CDD:410073	35/82 (43%)
		Daz	596..616	CDD:465893	3/6 (50%)
		Daz	620..640	CDD:465893
		Daz	644..664	CDD:465893
		Daz	668..688	CDD:465893
		Daz	692..712	CDD:465893