Protein Alignment bol and CSTF2

DIOPT Version :10

• Sequence 1: NP_001261614.1
• Gene: bol / 39049
• FlyBaseID: FBgn0011206
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_001293135.1
• Gene: CSTF2 / 1478
• HGNCID: 2484
• Length: 597
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 63/324 - (19%)
• Similarity: 98/324 - (30%)
• Gaps: 139/324 - (42%)

  Fly    35 IFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDR-AGVSKGYGFVTFETEQEA------------ 86
            :|||.|..:.||..|..:||..|.|.|.:::.|| .|..|||||..::.::.|
Human    18 VFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREF 82

  Fly    87 --QRLQAD-------------------------GECVVLRDRKLNIAPA---------------- 108
              :.|:.|                         ||.:...|...:|:.|
Human    83 SGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQM 147

  Fly   109 ---IKKQPNPLQSIVATNGAVYY------------------------TTTP------PAPI---- 136
               ::..|...::::..|..:.|                        |..|      |.|:
Human   148 KLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQTNIPTLIAGNPQPVHGAG 212

  Fly   137 ----SNIPMDQ-------------FAAAVYPPVTDFT-AAGVPA---------------IYPPSA 168
                ||:.|:|             ......||:...: ..||||               :.|...
Human   213 PGSGSNVSMNQQNPQAPQAQSLGGMHVNGAPPLMQASMQGGVPAPGQMPAAVTGPGPGSLAPGGG 277

  Fly   169 MQYQPFYQYYSVPMNVPTIWPQNYQENHSPLLHSPTSNPHSPHSQSHPQSPCWSIEDLRDTLPR 232
            ||.|         :.:|...|.:.:.....|.|||. .|..|.|....|.|   ::|.|..:.|
Human   278 MQAQ---------VGMPGSGPVSMERGQGTLQHSPV-GPAGPASIERVQVP---MQDPRAAMQR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bol	NP_001261614.1	RRM_DAZL_BOULE	31..111	CDD:409846	28/134 (21%)
		PABP-1234	<45..219	CDD:130689	55/299 (18%)
CSTF2	NP_001293135.1	PABP-1234	4..352	CDD:130689	63/324 (19%)
		RRM_CSTF2_CSTF2T	10..94	CDD:410072	23/75 (31%)
		CSTF2_hinge	112..191	CDD:433869	8/78 (10%)
		PHA03378	<253..455	CDD:223065	22/89 (25%)
		CSTF_C	553..593	CDD:464130