DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bol and HNRNPA0

DIOPT Version :9

Sequence 1:	NP_001261614.1	Gene:	bol / 39049	FlyBaseID:	FBgn0011206	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_006796.1	Gene:	HNRNPA0 / 10949	HGNCID:	5030	Length:	305	Species:	Homo sapiens

Alignment Length:	119	Identity:	37/119 - (31%)
Similarity:	58/119 - (48%)	Gaps:	16/119 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AAAPPPSATPGGGLETPLAAPKYGTLIP------NRIFVGGISGDTTEADLTRVFSAYGTVKSTK 63
            |.|..|.|..|..:|...|..:..:..|      .::||||:.||..|.||...||.:|||:..:
Human    64 AMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE 128

  Fly    64 IIVDR-AGVSKGYGFVTFETEQEAQRLQADGECVV----LRDRKLNIAPAIKKQ 112
            ||.|: :|..:|:|||.|:...     .||...||    ::..::.:..|:.|:
Human   129 IIADKQSGKKRGFGFVYFQNHD-----AADKAAVVKFHPIQGHRVEVKKAVPKE 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bol	NP_001261614.1	RRM_DAZL_BOULE	31..111	CDD:240858	29/90 (32%)
HNRNPA0	NP_006796.1	RRM1_hnRNPA0	5..83	CDD:240772	6/18 (33%)
		RRM2_hnRNPA0	99..178	CDD:241023	29/84 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..214		1/4 (25%)
		HnRNPA1	255..>269	CDD:314495
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910